190 citations,
October 2002 in “The FASEB journal” Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.
Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.
1 citations,
October 2022 in “Biomedicines” Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.
84 citations,
December 2008 in “Developmental biology” Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.
171 citations,
July 2007 in “Journal of Investigative Dermatology” A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
11 citations,
September 2014 in “International Journal of Molecular Sciences” Mycophenolate helps reverse hair loss effects caused by IFN-γ by activating a key hair growth pathway.
1 citations,
December 2011 Marine-derived ingredients show potential for hair health but need more human trials to confirm effectiveness.
August 2019 in “Research Square (Research Square)” Certain long non-coding RNAs in cashmere goats affect hair growth when treated with a specific growth factor.
1 citations,
January 2021 in “Skin appendage disorders” A woman with alopecia regrew her hair after taking a higher dose of tocilizumab.
14 citations,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
41 citations,
July 2012 in “Stem Cells and Development” Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.
18 citations,
July 2016 in “Medicine” Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.
4 citations,
January 2019 in “Archives of clinical and medical case reports” Combining FUE hair transplantation with PRP improves hair density and patient satisfaction in scarring alopecia.
1 citations,
August 2023 in “The Journal of Pathology” Different types of skin fibroblasts have unique roles in skin health and disease.
7 citations,
December 2021 in “Pharmaceutics” Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.
28 citations,
October 2013 in “Cornea” Scientists have made progress in creating replacement teeth, hair, and glands that work, which could lead to new treatments for missing teeth, baldness, and dryness conditions.
May 2021 in “Experimental Cell Research” FOXC1 boosts SFRP1 in hair loss, suggesting new treatments.
7 citations,
July 2019 in “International Journal of Molecular Sciences” PGA-4HGF may help treat hair loss by activating hair growth pathways and extending the hair growth phase.
August 2023 in “Stem Cell Research & Therapy” Using adipose-derived stem cell media with minoxidil may help regrow hair in men with hair loss.
3 citations,
July 2011 in “Expert Review of Dermatology” Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.
8 citations,
January 2022 in “Burns and trauma” Skin cell-derived vesicles can help heal skin injuries effectively.
1 citations,
September 2019 in “Journal of Investigative Dermatology” Human hair matrix cells and dermal papilla fibroblasts can form early hair follicle structures but don't produce hair shafts yet.
2 citations,
January 2017 in “International journal of genetics and genomics” Certain miRNAs are linked to chicken feather development.
September 2016 in “Journal of dermatological science” Human induced pluripotent stem cells can be used to create cells that help grow hair.
1 citations,
January 2019 in “Annals of dermatology/Annals of Dermatology” STAT5 is crucial for hair growth in 3D cultured human dermal papilla cells.
April 2018 in “Journal of Investigative Dermatology” Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.
138 citations,
June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
8 citations,
July 2019 in “Cell Proliferation” Researchers found a way to turn skin cells into cells that can grow new hair.
1 citations,
April 2017 in “Journal of Investigative Dermatology” CCL5 is important for the hair growth potential of human dermal papilla cells.
July 2022 in “Journal of Investigative Dermatology” Blocking DPP4 can help activate hair growth and improve hair regeneration.