91 citations,
December 2000 in “The journal of cell biology/The Journal of cell biology” Scientists successfully created mouse hair proteins in the lab, which are stable and similar to natural hair.
20 citations,
August 2005 in “The Journal of laboratory and clinical medicine” Mice with damaged skin or hair follicles are more susceptible to anthrax infection.
11 citations,
August 2021 in “Stem Cell Research & Therapy” The document concludes that using a person's own fat cells (SVF) can significantly increase hair thickness and density, suggesting it could be a promising treatment for hair loss.
2 citations,
July 2021 in “Genes” A specific genetic change in the KRT71 gene causes a hair loss condition in Hereford cattle.
1 citations,
December 2022 in “Archives of Dermatological Research” SVF injections improve hair growth and reduce hair loss in people with androgenic alopecia.
1 citations,
October 2021 in “Clinical, Cosmetic and Investigational Dermatology” Vitamin B3 may help prevent hair loss and promote hair growth by protecting scalp cells from stress and reducing hair growth-blocking proteins.
February 2024 in “Plastic and Reconstructive Surgery – Global Open” Stem cell therapies show promise for hair regrowth in androgenetic alopecia.
Stem cell treatments show promise for hair loss but need more research.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
124 citations,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
117 citations,
April 2008 in “Developmental biology” Ectodysplasin inhibits Wnt signaling to help form hair follicles.
68 citations,
April 2014 in “Journal of Investigative Dermatology” Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.
53 citations,
April 2016 in “Stem cell research & therapy” LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.
49 citations,
November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
28 citations,
November 2018 in “Journal of Cellular and Molecular Medicine” CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
27 citations,
November 2007 in “Genomics” Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.
12 citations,
January 2021 in “International Journal of Biological Sciences” Scientists successfully edited a goat's genes to grow more and longer cashmere hair.
7 citations,
February 2022 in “Journal of Personalized Medicine” Platelet-Rich Plasma therapy significantly increases hair density in people with Androgenic Alopecia, and works better with more treatments per month and in younger patients.
2 citations,
June 2022 in “Cosmoderma” Regenerative medicine shows promise for improving hair and skin but needs more research for standard use.
January 2009 in “Egyptian Journal of Medical Human Genetics” The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.
10 citations,
November 2021 in “International journal of molecular sciences” Sheep and goat hair fibers are complex due to keratin-associated proteins, which are important for fiber properties and growth.
276 citations,
April 2003 in “Molecular endocrinology” Vitamin D is important for bones, hair, blood pressure, and breast development.
86 citations,
April 2009 in “Journal of anatomy” Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
22 citations,
July 2020 in “iScience” Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.
489 citations,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
163 citations,
October 2001 in “EMBO journal” Overexpressing follistatin in mice delays wound healing and reduces scar size.
151 citations,
June 2010 in “Endocrinology and metabolism clinics of North America” Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.
32 citations,
December 2019 in “The Journal of clinical investigation/The journal of clinical investigation” A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
31 citations,
November 2020 in “International journal of molecular sciences” Adipokines affect skin health and could be targeted for treating skin diseases.
18 citations,
June 2001 in “Journal of Investigative Dermatology” Adding a specific gene to skin cells can help treat skin disorders like psoriasis.