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The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

New effective scar treatments are urgently needed due to the current options' limited success.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Skin fat helps with body temperature control and has other active roles in health.

Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Advanced human skin models improve drug development and could replace animal testing.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Wnt signaling is crucial for skin wound healing and reducing scars.

Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.

The study found key genes and pathways involved in cashmere goat hair growth stages.

Spermidine may help reduce hair loss and deserves further testing as a treatment.

Root hair growth in plants is a complex process controlled by many factors working together.

Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.

Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.

Estrogen can temporarily slow down hair growth but this can be reversed.

SIRT7 protein is crucial for starting hair growth in mice.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.

Boosting β-catenin signaling in certain skin cells can enhance hair growth.