research Male Androgenetic Alopecia
Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.
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research Pannexin 3 Regulates Skin Development via Epiprofin
Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.
research Topical L-Thyroxine: The Cinderella Among Hormones Waiting to Dance on the Floor of Dermatological Therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
research DNMT1-Mediated Methylation Inhibits MicroRNA-214-3p and Promotes Hair Follicle Stem Cell Differentiation Into Adipogenic Lineages
DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
research Androgenetic Alopecia, Trichotrophic Substances, and Histologic Studies of the Human Scalp
Minoxidil promotes hair growth but exact mechanism is unknown.
research Hair Loss Disorders in Domestic Animals
The book explains causes, diagnosis, and treatments for hair loss in pets.
research Kartogenin Regulates Hair Growth and Hair Cycling Transition
Kartogenin may help treat hair loss by promoting hair growth and extending the hair growth phase.
research A Novel Hair Restoration Technology Counteracts Androgenic Hair Loss and Promotes Hair Growth in a Blinded Clinical Trial
A new hair restoration technology was found to effectively increase hair thickness, density, and growth, while reducing hair loss and improving scalp health, with no side effects.
research SOX2 in the Skin: Roles in Biology and Pathology
SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
research Differential Expression of Keratin and Keratin Associated Proteins Are Linked with Hair Loss Condition in Spontaneously Mutated Inbred Mice
The study investigates hair loss in spontaneously mutated inbred C57BL/6 mice, which exhibit a delayed catagen phase in the hair cycle, leading to cyclic alopecia. The research identifies significant differential expression of genes related to keratinization, such as Krt16, Alox15, and Msx2, with Krt6b levels notably higher in hair loss mice across all hair cycle stages. These findings suggest that the abnormal expression of these genes contributes to the hair loss phenotype. The study provides a model for understanding hair loss mechanisms and developing potential treatments for alopecia.
research Water Extract of Cacumen Platycladi Promotes Hair Growth Through the Akt/GSK3β/β-Catenin Signaling Pathway
Water extract of Cacumen Platycladi helps hair growth by activating specific cell pathways.
research Defining Dermal Adipose Tissue
Skin fat cells help with skin balance, hair growth, and healing wounds.
research Histopathology of Non-Scarring Alopecia
The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
research New Investigational Drugs for Androgenetic Alopecia
Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
research Lymphoid Enhancer-Binding Factor-1 Interacts with the DNA-Binding Domain of the Vitamin D Receptor
LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
research Glutamate Transporter SLC1A3 Mediates Inter-Niche Stem Cell Activation During Skin Growth
The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Costunolide Promotes the Proliferation of Human Hair Follicle Dermal Papilla Cells and Induces Hair Growth in C57BL/6 Mice
Costunolide helps human hair cells grow and can stimulate hair growth in mice.
research Stem Cells from Human Exfoliated Deciduous Teeth Promote Hair Regeneration in Mice
Baby teeth stem cells can help grow hair in mice.
research Generation of Trichogenic Adipose-Derived Stem Cells by Expression of Three Factors
Scientists made stem cells that can grow hair by adding three specific factors to them.
research Comprehensive Transcriptome Profiling of Balding and Non-Balding Scalps in Trichorhinophalangeal Syndrome Type I Patient
The study found genetic differences related to hair development that may explain hair loss in a patient with Trichorhinophalangeal syndrome type I.
research Culturing of Melanocytes from the Equine Hair Follicle Outer Root Sheath
Researchers successfully grew horse skin cells that produce pigment from hair follicle samples.
research Autophagy Dysfunction: The Kernel of Hair Loss?
Manipulating cell cleanup processes could help treat hair loss.
research Deciphering the Molecular Mechanisms of Stem Cell Dynamics in Hair Follicle Regeneration
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
research Hair Growth Promotion and Anti-Hair Loss Effects of Arabica Coffee Pulp Extracts Using Supercritical Fluid Extraction
Arabica coffee pulp extract may help prevent hair loss and promote hair growth.
research Functional Mapping of the Mouse Hairless Gene Promoter Region
Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
research Identification of Novel Hair-Growth Inducers by Means of Connectivity Mapping
The study aimed to identify new hair-growth inducers using connectivity mapping (Cmap) and gene expression profiling. Researchers analyzed gene expression in mice treated with cyclosporin A (CsA), a known hair-growth inducer, and identified several agents with similar gene signatures. Fluphenazine, identified from the day 2 signature, successfully induced hair growth in vivo, and its effect was enhanced by subsequent application of iloprost, identified from the day 4 signature. The study demonstrated that Cmap analysis was effective in linking gene expression profiles to potential hair-growth agents, suggesting a promising method for discovering treatments for hair cycle disorders.
research Distinct Mechanisms Underlie Pattern Formation in the Skin and Skin Appendages
Different processes create patterns in skin and things like hair and feathers.
research The Effects of Extracellular Matrix and Growth Factors on Dermal Papilla Cell Proliferation
Different substances affect hair and skin cell growth in various ways.
research Platelet-Rich Plasma and Its Use for Cicatricial and Non-Cicatricial Alopecias: A Narrative Review
Platelet-Rich Plasma (PRP) can promote new hair growth and increase hair density, but its effectiveness varies depending on the type of hair loss.