February 2026 in “Journal of the Korean Society of Cosmetology” This study found that the viscosity of silicone oil in hair treatments significantly affects wave curling performance and hair damage, with untreated and chemically treated hair showing different optimal viscosities.
85 citations
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October 2007 in “International Journal of Dermatology” In this study, researchers found that the curliness of human hair is associated with an asymmetric structure at the cellular level, particularly in the differentiation of the precortex.
In this study conducted at Shafa Hospital, Kerman, Iran, 3.5% of patients using sodium valproate as an antiepileptic experienced hair loss and curling over ten years.
65 citations
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March 2017 in “Experimental Dermatology” This review discusses the genetic and biological factors influencing hair curliness, revealing strong links to specific protein variations, and reports no new clinical results.
This study examined hair classification based on geo-racial origin, observing that Caucasian and Mediterranean hair differs morphologically from African or Asian hair, with differences in density, thickness, and fiber shape contributing to varied hair characteristics such as color and curliness.
This research explores the use of serial block-face scanning electron microscopy to model the complex architecture of sheep wool fibres, focusing on the role and distribution of para- and ortho-cortical cells in determining wool curliness, though the mechanism remains unclear.
In this research, the author hypothesizes that curly hair is influenced by the contraction of the Arrector Pili muscle, suggesting that its relaxation through specific treatments could potentially modulate hair follicle curvature, but further studies are needed to confirm this mechanism.
January 1993 in “Inpharma Weekly” A new food supplement was highly effective in curing hair loss in young men.
4 citations
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June 2022 in “Clinical, cosmetic and investigational dermatology” In this study, researchers introduced the Sanusi FUE Score Scale to better predict and grade the difficulty of follicular unit excision hair transplantation by accounting for diverse hair and skin types, with further validation needed.
January 2016 in “International journal of clinical pediatrics” In this study, ultrastructural examination of hair in children treated with valproic acid showed a normal hair surface and cuticular pattern, despite reported hair changes with the drug.
9 citations
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July 2016 in “The Journal of Dermatology” This letter to the editor discusses an observed case of hair repigmentation linked with etretinate therapy but reports no new research findings.
January 2024 in “Indian Journal of Pharmaceutical Sciences” This study hypothesizes that curly hair is shaped by the contraction of the Arrector Pili Muscle within the follicle, potentially modifiable through muscle-relaxing treatments, but further research is needed to confirm this mechanism.
3 citations
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November 2019 in “Clinical psychopharmacology and neuroscience/Clinical Psychopharmacology and Neuroscience” Valproate can cause both hair loss and curly hair in bipolar disorder patients.
February 2022 in “International journal of research in dermatology” This case series describes seven distinct hair shaft disorders, highlighting the importance of accurate diagnosis since these conditions are often treated incorrectly as alopecias without improvement.
40 citations
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February 1990 in “Journal of The American Academy of Dermatology” This study presents the first reported case of woolly hair nevus appearing during adolescence, with significant improvement observed 5 years later and structural changes in the hair documented.
October 2025 in “Journal of the Korean Society of Cosmetology” This study found that applying a hair mist with dandelion extract before heat perming improved wave efficiency, tensile strength, and hair cuticle condition compared to a base mist or no pretreatment, demonstrating the extract's protective effects against heat damage.
This study analyzed inner root sheath-specific genes in Tan sheep during various growth stages, finding peak expression at birth. The pattern of genes KRT71, KRT72, and TCHH is consistent with wool crimp, potentially influencing wool morphology.
October 2015 in “Cosmetic Dermatology” This article reviews the components and forms of hair styling aids, their safety, and potential use in improving appearance-related hair conditions but reports no new clinical findings.
February 2024 in “Tissue & Cell” This review evaluates recent advancements in hair follicle bioengineering and discusses the potential for developing effective treatments for hair loss through tissue engineering, despite current challenges in creating functional cultured human hair cells.
13 citations
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November 2012 in “International Journal of Dermatology” This study of African-American women found that those perceiving greater hair breakage showed lower break stress and higher premature failure rates, linked to grooming practices and hair curvature.
11 citations
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July 2021 in “Sustainability” In this study, researchers found that replacing natural aggregates with animal bones and human hair with increased microroughness may improve the mechanical strength and durability of concrete.
May 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A mutation in the KRT74 gene causes woolly hair by affecting hair texture.
May 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A mutation in the KRT74 gene causes woolly hair by affecting hair texture.
January 2026 in “International Journal of Dermatology” This review examines the androgen-dependent subtype of acquired progressive kinking of the hair and suggests it may be an early indicator of androgenetic alopecia, emphasizing the importance of distinguishing between subtypes for clinical decisions.
This article explores whether Melampus, a mythological healer, may have intentionally caused the madness of Proetus' daughters through the use of herbs, despite being credited with their cure.
February 2019 in “IP Indian journal of clinical and experimental dermatology” In this study, continuous use of chemical hair relaxers and curlers was associated with adverse effects such as hair fall, thinning, and scalp irritation in patients with telogen effluvium.
2 citations
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January 2017 in “International journal of genetics and genomics” This study identified specific miRNAs associated with hair follicle development in chicken embryos, highlighting miR-1623's involvement in regulating WNT4 and contributing to hair follicle cell growth.
4 citations
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January 2017 in “PubMed” This report describes a rare case of acquired eyelash trichomegaly in a 16-year-old female with systemic lupus erythematosus, accompanied by diffuse hair loss and "lupus hairs" on the scalp.
December 2021 in “International journal of minor fruits, medicinal and aromatic plants” This review identifies common medicinal plant species in Sri Lankan home gardens and discusses their traditional Ayurvedic uses, but it reports no new clinical results.
3 citations
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April 2021 in “GSC Biological and Pharmaceutical Sciences” This review discusses the traditional uses and reported bioactivities of Elephantopus scaber, but provides no new experimental results; the authors call for more research on its anticancer potential.