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DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Heavily hunted wolves have higher stress and reproductive hormone levels.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Medium-dose prednisolone pulse therapy is effective and safe for multifocal alopecia areata but not for more severe forms.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

The glucocorticoid receptor helps protect skin from tumors and other issues.

Alopecia greatly affects Greek women's daily life, relationships, and self-image, with mixed social support and dissatisfaction with treatments.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

MR antagonists may improve skin health and wound healing, especially in aging.

Eyelid cells share signaling components but differ in pathway activity.

Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.

Mesotherapy might be a useful addition to dental surgery to reduce drug use and side effects, but more research is needed.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Alopecia areata is an autoimmune disease with genetic links, treatable with certain medications, and can affect mental health.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Adult acne is often related to hormonal disorders, especially in women, and may need long-term treatment involving specialists.

Pregnancy with Cushing's syndrome is rare and risky for both mother and baby, needing early diagnosis and treatment.

Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.