85 citations,
October 2012 in “Dermatologic Clinics” Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.
37 citations,
August 2016 in “Clinical, Cosmetic and Investigational Dermatology” The document concludes that better treatments for CCCA are needed and more research is required to understand its causes related to hairstyling and genetics.
27 citations,
July 2018 in “Experimental dermatology” Autophagy is crucial for normal sebaceous gland function and sebum composition.
December 2013 in “Biomedical and biopharmaceutical research” Nanotechnology shows promise for better drug delivery and cancer treatment.
117 citations,
September 2003 in “Molecular & cellular proteomics” The technology can help diagnose and subtype autoimmune diseases by identifying specific autoantibodies.
28 citations,
December 2016 in “Journal of Biomedical Materials Research Part A” Bone-forming cells grow well in 3D polymer scaffolds with 35 µm pores.
6 citations,
December 2022 in “Colloids and Surfaces B: Biointerfaces” The new wound dressing promotes cell growth and healing, absorbs wound fluids well, and is biocompatible.
4 citations,
October 2022 in “Cell Reports Physical Science” New wound healing method using nanoparticles in a gel speeds up healing and reduces infection and inflammation.
522 citations,
January 2001 in “Cancer investigation” Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
203 citations,
May 2017 in “Journal of controlled release” Microneedles are being used and tested for various medical and cosmetic treatments.
156 citations,
August 2014 in “Cochrane library” Budesonide is not effective for maintaining remission in Crohn's disease beyond three months.
151 citations,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
96 citations,
September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
61 citations,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
61 citations,
June 2022 in “Journal of Controlled Release” Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
48 citations,
September 2020 in “Frontiers in Immunology” Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.
35 citations,
November 2021 in “Journal of nanobiotechnology” Thymol-loaded nanoparticles are a promising, natural treatment for acne that avoids antibiotics and preserves healthy skin bacteria.
33 citations,
December 2012 in “NMR in Biomedicine” Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.
32 citations,
June 2017 in “Journal of infection/The Journal of infection” The document concludes that terbinafine is effective for treating scalp fungal infections in children and recommends not excluding them from school during treatment, while also highlighting the need for updated treatment guidelines due to changing infection patterns.
31 citations,
September 2011 in “European journal of pharmaceutics and biopharmaceutics” PLA particles release their contents differently based on the type of fluorochrome used.
30 citations,
February 2022 in “Pharmaceutics” 3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
28 citations,
September 2021 in “EMBO reports” Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
28 citations,
January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems” Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.
22 citations,
March 2017 in “Journal of the Formosan Medical Association” The guidelines help doctors manage skin problems from certain cancer treatments to improve patients' lives.
21 citations,
January 2022 in “Biomaterials Science” RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
21 citations,
June 2022 in “Molecules” Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.
18 citations,
December 2021 in “Foods” Seaweeds contain beneficial compounds with potential uses in food, cosmetics, and health, but more research is needed to improve extraction and safety.
18 citations,
July 2022 in “Frontiers in Immunology” Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.
13 citations,
November 2022 in “Chemical Science” Inorganic-based biomaterials can quickly stop bleeding and help wounds heal, but they may cause issues like sharp ion release and pH changes.
10 citations,
September 2022 in “Advanced Healthcare Materials” Current methods can't fully recreate skin and its features, and more research is needed for clinical use.