research Human Keratinocytes Derived from the Bulge Region of Hair Follicles Are Refractory to Differentiation
Hair follicle cells resist turning into skin cells.
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research Stem Cell Markers (Cytokeratin 15, CD34, and Nestin) in Primary Scarring and Nonscarring Alopecia
Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.
research Human Skin Stem Cells and the Aging Process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair
Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
research Multi-Potentiality of a New Immortalized Epithelial Stem Cell Line Derived from Human Hair Follicles
Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
research Controlling the Stem Cell Niche: Right Time, Right Place, Right Strength
Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
research Epidermal Keratinocyte Stem Cells: Their Maintenance and Regulation
Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
research Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells
Wnt signaling is crucial for skin development and hair growth.
research Skin and Hair: Models for Exploring Organ Regeneration
Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
research The HPV16 Oncogenes Cause Aberrant Stem Cell Mobilization
HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
research Valentina Greco: Got Hair?
Valentina Greco's research shows that the environment around hair follicle stem cells is more crucial for regeneration than the stem cells themselves.
research Divergent Proliferation Patterns of Distinct Human Hair Follicle Epithelial Progenitor Niches In Situ and Their Differential Responsiveness to Prostaglandin D2
Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.
research State-Dependent Signaling by Cav1.2 Regulates Hair Follicle Stem Cell Function
Cav1.2 affects hair growth and could be a target for hair loss treatments.
research Keratin K15 as a Biomarker of Epidermal Stem Cells
Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
research Meis1 Regulates Epidermal Stem Cells and Is Required for Skin Tumorigenesis
Meis1 is crucial for skin health and tumor development.
research Principles and Mechanisms of Regeneration in the Mouse Model for Wound-Induced Hair Follicle Neogenesis
Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
research Reflections on How Wound Healing-Promoting Effects of the Hair Follicle Can Be Translated into Clinical Practice
Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.
research The Rho Guanosine Nucleotide Exchange Factors Vav2 And Vav3 Modulate Epidermal Stem Cell Function
Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
research Compartmentalized Organization: A Common and Required Feature of Stem Cell Niches?
Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
research CD34 Defines Melanocyte Stem Cell Subpopulations With Distinct Regenerative Properties
CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
research Regenerating the Skin: A Task for the Heterogeneous Stem Cell Pool and Surrounding Niche
Different types of stem cells and their environments are key to skin repair and maintenance.
research Embryonic-Like Regenerative Phenomenon: Wound-Induced Hair Follicle Neogenesis
New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
research Distinct Mechanisms for Sebaceous Gland Self-Renewal and Regeneration Provide Durability in Response to Injury
Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.
research Three Streams for the Mechanism of Hair Graying
Hair graying may be caused by stem cell depletion from stress or melanocyte damage.
research The Arrector Pili Muscle: The Bridge Between the Follicular Stem Cell Niche and the Interfollicular Epidermis
The study suggests that the arrector pili muscle is important for hair health and its damage might contribute to hair loss.
research Identification of the Cell Lineage at the Origin of Basal Cell Carcinoma
Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
research Single-Cell Profiling Reveals a Potent Role of Quercetin in Promoting Hair Regeneration
Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.
research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis Through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance
The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis
Notch signaling is essential for healthy skin and hair follicle maintenance.
research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.