September 2019 in “Journal of Investigative Dermatology” IL-17 and certain immune cells are linked to more severe alopecia areata.
2 citations,
April 2021 in “International Journal of Pharmaceutics” Serum formulations were better at delivering molecules to the hair bulb than nanoparticles.
40 citations,
March 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.
20 citations,
August 2015 in “International Journal of Molecular Medicine” Human placental extract may help hair growth by affecting certain cell signals and could be more effective with minoxidil.
9 citations,
April 2019 in “International journal of molecular sciences” Human hair grows better in a special gel that mimics skin.
165 citations,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
3 citations,
July 2011 in “Folia Histochemica et Cytobiologica” Calcium reduces involucrin in rat hair bulbs but doesn't affect filaggrin and Kdap.
3 citations,
November 2011 in “European Journal of Dermatology” 4-O-methylhonokiol from Magnolia officinalis significantly promotes hair growth.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.
3 citations,
April 2016 in “Food Science and Biotechnology” Oriental melon leaf extract may help hair grow and keep it in the growing phase longer.
86 citations,
May 2002 in “Journal of Investigative Dermatology” A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
Chrysanthemum zawadskii extract may help treat hair loss by promoting hair growth and affecting growth factors.
December 2024 in “Biological and Pharmaceutical Bulletin” Gum arabic improves minoxidil delivery to hair follicles, enhancing hair growth.
9 citations,
September 2013 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.
130 citations,
January 1994 in “Differentiation” Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
5 citations,
July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Proteolytic enzymes damage hair follicles by detaching stem cells.
14 citations,
October 2020 in “Scientific reports” Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
August 2023 in “International Journal of Molecular Sciences” The human scalp hair bulb contains different types of melanocytes with varying abilities to produce melanin.
314 citations,
April 2010 in “Developmental Cell” β-catenin in the dermal papilla is crucial for normal hair growth and repair.
48 citations,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
15 citations,
September 1999 in “British Journal of Dermatology” Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
2 citations,
December 2023 in “Royal Society of Chemistry eBooks” Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
7 citations,
May 2020 in “Trends in molecular medicine” The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
5 citations,
November 2008 in “Advances in Dermatology” The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.
Daily hair care may cause holes in hair fibers.
22 citations,
June 2013 in “Australasian Journal of Dermatology” Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.
5 citations,
September 2012 in “Springer eBooks” Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
2 citations,
February 2015 in “Journal of Tissue Engineering and Regenerative Medicine” Transplanting a mix of specific skin cells can significantly improve the repair of damaged hair follicles.
September 2017 in “Asian Journal of Beauty and Cosmetology” The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.