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Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.

Hair restoration has evolved from surgery to drugs to potential gene therapy, with improved results and ongoing research driven by high demand.

There is an urgent need for better treatments for hair loss caused by chemotherapy.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Hair usually grows back 1-3 months after treatment for anagen effluvium, and children with Loose Anagen Hair Syndrome often improve by adolescence.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

The document suggests that certain protein deficiencies and scalp blistering in Epidermolysis Bullosa may cause hair loss.

VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.

Minoxidil can help thicken hair in some people with male pattern baldness, especially if used early and continuously.

Restoring immune privilege in hair follicles could help treat certain types of hair loss.

Plasmalogens activate a channel in cells that may stimulate hair growth.

Rice water and hibiscus can help improve hair health and growth.

Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.

LLLT increases hair density and growth in AGA patients.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Platelet-rich plasma (PRP) is a cheap and easy treatment for hair loss, but not suitable for everyone. It also helps in healing ulcers, rejuvenating skin, and improving hair transplants.

Certain genes control the color of human hair by affecting pigment production.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.

Ketoconazole shampoo with finasteride improves hair density in men with hair loss.

Researchers developed a method to grow hair follicle cells for transplantation using a special chip.

Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.