September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported that while eyebrow hair transplantation in patients with frontal fibrosing alopecia achieves satisfactory short-term results, most patients experience significant hair graft loss within 3-4 years.
This study found that in a rat model of alopecia, combining low-level laser therapy with Neoptide treatment resulted in better hair regrowth compared to either treatment used alone.
11 citations
,
January 2014 in “The Scientific World Journal” This study found that Cynatine HNS significantly improved hair and nail health in women after 90 days compared to placebo.
7 citations
,
August 2018 in “Journal of cosmetic dermatology” This study found that chemical hair straightening significantly reduced hair curl and improved smoothness and shine, but did not significantly affect transverse fissures or split ends, indicating potential benefits with some side effects.
3 citations
,
January 2017 in “Journal of cosmetology & trichology” This study reports that a nutritional complex may improve hair density and quality, with in vitro findings demonstrating inhibition of 5α-reductase, and participants noting reduced hair loss and greasiness.
1 citations
,
May 2001 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This paper presents an RGB video microscopic system to monitor optical properties of hair shafts and follicles in vitro, but reports no new clinical results.
November 2021 in “Egyptian Journal of Medical Microbiology” This study found that protective measures against COVID-19, such as prolonged mask-wearing and frequent hand washing, were associated with skin issues, hair loss, and nail brittleness among participants in Iraq.
1 citations
,
June 2024 in “International Journal of Drug Delivery Technology” This review suggests that herbal hair serums, which are claimed to nourish the scalp and promote hair growth, may effectively treat alopecia without adverse effects, offering a natural alternative to allopathic medications that often have side effects.
This study analyzes the application of a new hair serum incorporating natural ingredients like Aloe vera and ginger, finding it potentially beneficial for managing hair frizz, improving smoothness, and preventing damage without significant adverse reactions.
208 citations
,
January 2013 in “Lab on a Chip” The researchers described a chip-based bioreactor platform for dynamic perfusion, which may enhance in vitro skin models by introducing mechanical shear stress and extending culture periods.
161 citations
,
July 2003 in “ACM Transactions on Graphics” In this study, a new shading model for hair was developed that better matches real-life light scattering, thanks to detailed new measurements of hair fiber scattering not predicted by existing models.
159 citations
,
September 2001 in “European Journal of Cancer Care” This literature study reviews the consequences of hair loss due to chemotherapy and nursing care interventions but reports no new clinical results.
103 citations
,
November 2014 in “Journal of Cell Biology” This study found that overexpression of miR-214 in keratinocytes inhibits hair follicle development and cycling by targeting β-catenin in the Wnt signaling pathway.
This study introduced a new hair shading model that more accurately simulates light scattering on hair fibers, capturing effects not predicted by previous models.
61 citations
,
December 2016 in “The EMBO Journal” This study established a new in vitro culture system that supports the growth and dynamic self-organization of hair follicle stem cells and their progeny, promoting a stable population equilibrium.
60 citations
,
January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that inhibiting PKC-β activity with bisindolylmaleimide reduces pigmentation in the skin and hair of guinea pigs and mice by preventing tyrosinase activation.
57 citations
,
August 2003 in “British Journal of Dermatology” This study found that daily use of 1% pyrithione zinc shampoo modestly improved hair growth over 26 weeks, although these effects were less than those of 5% minoxidil.
51 citations
,
September 2020 in “Cell Metabolism” This study highlights that the mammalian target of rapamycin complex 2 (mTORC2)-Akt signaling axis is essential for hair follicle stem cells to return to their niche and regenerate effectively by regulating metabolic pathways.
47 citations
,
January 2017 in “RSC Advances” Keratin peptides can change hair shape gently without harsh chemicals.
44 citations
,
March 2016 in “Frontiers in cellular neuroscience” In this study using zebrafish, four bisbenzylisoquinoline derivatives were found to protect hair cells from aminoglycoside-induced damage without reducing antibiotic efficacy, potentially leading to therapies for patients undergoing such treatments.
40 citations
,
March 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study visualized mitochondrial metabolism in cultured bovine hair follicles and plucked human hairs, finding that ROS and mitochondrial polarization correlate in specific hair follicle regions, particularly near keratin deposition sites.
39 citations
,
December 2011 in “PLoS ONE” This study reported that exposure to 1,763 MHz radiofrequency radiation stimulated hair growth in vitro by inducing insulin-like growth factor-1 expression in cultured human dermal papilla cells.
31 citations
,
February 2014 in “Journal of dermatological science” This study found that placental growth factor (PlGF) enhanced hair shaft elongation and accelerated hair follicle growth, suggesting its potential as a therapeutic target for alopecia.
29 citations
,
December 2016 in “The EMBO Journal” This study found that the transcription factor Gata6 plays a crucial role in adult mouse hair follicle regeneration by promoting the renewal and preventing DNA damage of rapidly proliferating progenitor cells.
28 citations
,
December 2011 in “Biocatalysis and biotransformation” This study found that a peptide treatment using Protein disulphide isomerase improved the mechanical and thermal properties of over-bleached hair by promoting deeper peptide penetration and attachment.
27 citations
,
April 2011 in “International journal of legal medicine” This study reports that the completeness of DNA degradation in hair during cornification varies among individuals and affects the success rates of forensic hair DNA analysis.
24 citations
,
April 2012 in “Developmental Biology” This animal study found that dermal papilla cells in hair follicles of chimeric mice can originate from various fibroblasts in the skin, challenging assumptions about their specific lineage.
23 citations
,
January 2016 in “Theranostics” In this animal study, ultrasound combined with a new microbubble formulation of minoxidil increased hair growth rates and improved follicle characteristics more effectively than minoxidil alone.
21 citations
,
October 2011 in “PloS one” In this study, researchers identified three molecules in hair that varied with age, suggesting potential markers for aging and targets for cosmetic products.
18 citations
,
December 2016 in “Phytomedicine” In this study, applying 1% or 5% Curcuma aeruginosa essential oil lotion to the underarm for 10 weeks significantly slowed hair growth and brightened skin in young women, with no adverse effects reported.