research Targeting Host Cell Proteases as a Potential Treatment Strategy to Limit the Spread of SARS-CoV-2 in the Respiratory Tract
Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.
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research The Role of Therapy in Impairing Quality of Life in Dermatological Patients: A Multinational Study
Skin treatment can lower life quality for patients with skin conditions.
research Lupus Erythematosus: Considerations About Clinical, Cutaneous, and Therapeutic Aspects
Lupus treatment requires a combination of drugs and therapies, with research needed for new options.
research Under Development JAK Inhibitors for Dermatologic Diseases
New JAK inhibitor drugs show promise for treating skin diseases but need more research on safety and effectiveness.
research Spontaneous Cutaneous Adverse Drug Reaction Reports: An Analysis of a 10-Year Dataset in Singapore
In Singapore, most skin reactions to drugs were in females and Chinese, often caused by painkillers, antibiotics, and some other drugs, with serious cases linked to genetics.
research Compilation of a Comprehensive Gene Panel for Systematic Assessment of Genes That Govern an Individual’s Drug Responses
Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.
research Development and Validation of a New Gas Flame Ionization Detector Method for the Determination of Finasteride in Tablets
New method accurately measures finasteride in tablets.
research Preparing Regenerative Therapies for Clinical Application: Proposals for Responsible Translation
The document suggests a need for collaboration, better evidence, and a responsible framework to safely and effectively advance regenerative therapies to clinical use.
research Male Fertility and Skin Diseases
Some skin diseases and their treatments can negatively affect male fertility.
research Tailored Chromatin Modulation to Promote Tissue Regeneration
Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
research The E6/E7 Oncogenes of Human Papillomavirus and Estradiol Regulate Hedgehog Signaling Activity in a Murine Model of Cervical Cancer
HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.
research Successful Treatment of Palmoplantar Pustular Psoriasis with Brodalumab
Brodalumab effectively treated a man's severe hand and foot psoriasis.
research Bioactivity Guided Isolation and Characterization of the Phytoconstituents from Tridax Procumbens
Tridax procumbens plant parts boost immune response in mice.
research The Association Between Serum Ferritin and 25-Hydroxyvitamin D and Metabolic Syndrome in Korean Women: The Korea National Health and Nutrition Examination Survey 2010–2012
Higher vitamin D levels are linked to higher iron levels in Korean women without metabolic syndrome, but not in those with it.
research Spherical Nucleic Acids as Emerging Topical Therapeutics: A Focus on Psoriasis
New topical treatment using spherical nucleic acids shows promise in reducing psoriasis inflammation.
research Challenging Regional Psoriasis and Ustekinumab Biotherapy: Impact of the Patterns of Disease
Ustekinumab might work for severe psoriasis, but more research is needed to be sure.
research Acrodermatitis Continua Resistant to Etanercept: Therapeutic Challenge and Unfortunate Outcome
A man with Acrodermatitis continua did not get better with etanercept treatment, and his condition worsened, suggesting treatment effectiveness may vary by genetics and race.
research The Osler Lecture 2012: Pharmacology 2.0, Medicines, Drugs, and Human Enhancement
The lecture concluded that drugs for human enhancement are here to stay and called for their responsible development and fair access.
research Optimal Management of Plaque Psoriasis in Adolescents: Current Perspectives
The document concludes that proper treatment and management of plaque psoriasis in adolescents can improve their quality of life.
research Comprehensive Overview of Rheumatology Studies: Ottawa, Ontario, Canada, February 13–16, 2013
The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.
research Impact of Clinical Response on Different Approved Doses in Japan and the United States
Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.
research Abstracts
Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.
research The Role of Entrepreneurial Leadership and Innovation in the Future of Therapeutic Dermatology
Entrepreneurial companies are key to advancing dermatology treatments and patient care.
research Treatment of Hidradenitis Suppurativa Evaluation Study: The THESEUS Prospective Cohort Study
Laser treatment and deroofing are effective options for hidradenitis suppurativa.
research Perifolliculitis Capitis Abscedens Et Suffodiens Treatment With Tumor Necrosis Factor Inhibitors and Baricitinib: A Case Report and Literature Review
A 15-year-old boy's severe scalp condition improved significantly with adalimumab and baricitinib treatment.
research Defining Chronic Wound Types in Recessive Dystrophic Epidermolysis Bullosa Patients for Clinical Outcome Assessment
The conclusion is that differentiating wound types in RDEB patients is important for clinical trials and understanding the disease.
research Development of Uniform Protocol for Alopecia Areata Clinical Trials
A standard protocol for alopecia areata clinical trials was created to improve consistency and encourage more research.
research Scientific Precision in Titles of Research Papers Published in Three Dermatology Journals
Many research paper titles in dermatology journals lack scientific precision.
research Scaffolds for Epidermal Tissue Engineering
New scaffold materials help heal severe skin wounds and improve skin regeneration.
research Industry Update: The Latest Developments in the Field of Therapeutic Delivery, July 2018
New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.