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Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

New treatments targeting specific genes show promise for treating keratin disorders.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Smoking may contribute to hair loss in men.

Men with hair loss experience lower quality of life, worsened by factors like age, severity, and treatment history.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Too much male hormone is the main cause of Polycystic Ovary Syndrome.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Fatty acid transport protein 4 is essential for skin and hair development.

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Certain mice without specific receptors or mast cells don't lose hair from stress.

Targeting the skin's endocannabinoid system could help treat skin disorders.