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Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

New therapies are being developed that target integrin pathways to treat various diseases.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

RANKL causes lymph nodes to grow by making certain cells multiply.

Teriflunomide effectively reduces relapse rates and disease progression in multiple sclerosis but is not safe for use during pregnancy.

sPLA2-X is crucial for normal hair growth and follicle health.

Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.

Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.

Vitamin D is crucial for bone health and preventing serious diseases.

PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

Microbial biosurfactants could be a safer and environmentally friendly alternative to chemical surfactants in cosmetics.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

Transglutaminase activity is important for skin and is found in both mammals and birds.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

ALRV5XR significantly improves hair density in women with hair loss and is well-tolerated.

High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.

Retinoic acid affects male and female muscle energy use and function differently.

Mice with alopecia areata had wider lymphatic vessels in their skin.

Our microbiome may affect the development of the hair loss condition Alopecia Areata, but more research is needed to understand this relationship.

Healthy lifestyle changes can significantly improve skin health as you age.