15 citations
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June 2015 in “Human Cell” This study found that forming spheroids using silicone micro-wells improved the viability and neural differentiation potential of human adipose-derived stem cells after thawing.
148 citations
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August 2022 in “Stem Cell Research & Therapy” This study found that encapsulating hADSCs-derived exosomes in PF-127 hydrogel improved wound healing in mice, suggesting a promising approach for enhancing skin repair.
28 citations
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January 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” This study found that Greek adult women with scarring alopecia experience more significant psychological burden and quality of life impairment compared to those with non-scarring alopecia.
27 citations
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January 2020 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This abstract outlines a questionnaire study conducted among doctors and nurses in Turkey during the early days of the COVID-19 outbreak, but it provides no new results.
18 citations
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May 2022 in “Stem Cell Research & Therapy” This study found that irradiating human adipose-derived stem cells with green OLEDs enhanced their wound healing capability and increased cell proliferation, migration, and adhesion in preclinical models.
4 citations
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October 2023 in “Journal of clinical medicine” This meta-analysis found that women with polycystic ovary syndrome have over a 2.5-fold higher risk of depression compared to healthy women.
3 citations
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January 2025 in “Biomaterials Science” In this study, blue light-irradiated nanovesicles derived from human adipose-derived stem cells enhanced dermal fibroblast proliferation and extracellular matrix synthesis, improving skin maintenance and hair follicle regeneration, suggesting a novel therapeutic strategy for skin and hair disorders.
1 citations
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November 2025 in “Journal of Health Psychology” This study found that individuals with Alopecia Areata experience significantly higher social appearance anxiety compared to healthy controls, driven more by appearance-related concerns than by general anxiety or depression, highlighting the importance of targeted psychosocial assessments in their routine care.
1 citations
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March 2023 in “International Wound Journal” This article reviewed a study suggesting that CCN1 secreted by human adipose-derived stem cells may enhance wound healing, although the authors note limitations such as small sample size and incomplete evaluation of wound healing processes.
January 2026 in “International Journal of Clinical Practice” This study found that individuals with alopecia areata have higher levels of anxiety and depression compared to healthy individuals, with longer disease duration linked to increased anxiety and severe severity predicting higher depression.
September 2025 in “Cyprus Journal of Medical Sciences” In this study, patients with acute alopecia areata experienced significantly higher anxiety and depression levels, along with a worsened quality of life, compared to a control group, underscoring the importance for clinicians to address these psychiatric issues early in the condition.
September 2025 in “Journal of the American Academy of Dermatology” Eyebrow and eyelash hair loss in alopecia areata worsens quality of life.
August 2025 in “Libyan Medical Journal” This study found that patients with vitiligo or alopecia areata have higher levels of anxiety and depression compared to healthy individuals, though no significant differences were observed between the two patient groups, highlighting the psychological impact of these dermatological conditions.
June 2024 in “British Journal of Dermatology” This study reported that while both DLQI and HADS showed moderate correlations, only DLQI correlated with clinician-assessed disease severity in patients with alopecia.
November 2023 in “JEADV Clinical Practice” In this study, adults with severe alopecia areata experienced greater improvements in hair regrowth, health-related quality of life, and reduced anxiety and depression symptoms after 36 weeks of treatment with baricitinib compared to placebo.
January 2026 in “Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna)” This study observed that baricitinib led to significant hair regrowth and improved psychological well-being in severe alopecia areata patients over 48 weeks, with 63.2% achieving a SALT score of ≤20.
April 2023 in “Journal of Investigative Dermatology” This study found that short-term NB-UVB treatment significantly reduced anxiety levels in psoriasis patients, but not depression.
April 2026 in “Biomaterials and Biosystems” This study found that combining multiple low-dose exosome injections with NIR-II-responsive selenium telluride-mediated photothermal therapy significantly improved healing in diabetic mice with pressure ulcers, enhancing wound closure, hair follicle regeneration, and collagen remodeling compared to single high-dose exosome treatment.
May 2025 in “World Journal of Stem Cells” This study discusses the potential of exosomes from human adipose-derived mesenchymal stem cells in enhancing dermal papilla cell proliferation via the Wnt/β-catenin pathway, suggesting a novel treatment approach for androgenetic alopecia by counteracting excessive dihydrotestosterone effects.
March 2025 in “World Journal of Stem Cells” This study found that human adipose-derived MSC exosomes (hADSC-Exos) may enhance dermal papillary cell proliferation and migration by activating the Wnt/β-catenin signaling pathway, potentially reversing the effects of dihydrotestosterone in androgenetic alopecia.
January 2023 in “Dermatologic Therapy” This study demonstrates a significant correlation between anxiety, depression, and reduced quality of life in individuals with androgenetic alopecia.
October 2022 in “Journal of Cosmetic Dermatology” This study found that hair transplantation surgery significantly improved loneliness, anxiety, and depression in patients, with notable score reductions in these psychosocial outcomes post-surgery.
187 citations
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April 2019 in “npj Regenerative Medicine” This study found that hMSC secretomes from umbilical cord Wharton's jelly had the most potent angiogenic effects, whereas those from adipose tissue demonstrated the weakest angiogenic potential.
35 citations
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July 2015 in “Journal of Affective Disorders” This study found that women with polycystic ovary syndrome have significantly higher scores for affective temperaments and anxiety and depression than healthy controls, suggesting risk for depressive and anxiety disorders.
4 citations
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March 2023 in “SKIN The Journal of Cutaneous Medicine” This abstract does not provide specific results or a conclusion; additional context is needed to interpret the data.
November 2025 in “Journal of Clinical Medicine” The researchers reported that baricitinib treatment for at least 52 weeks reduced severe alopecia areata severity and improved psychological well-being and quality of life in study participants.
September 2025 in “Journal of the European Academy of Dermatology and Venereology” This real-world study found that baricitinib 4 mg daily was effective in promoting hair regrowth and improving psychological well-being in Italian adults with severe alopecia areata over 48 weeks, with 63.2% of patients achieving significant hair recovery and 9.4% experiencing adverse events.
August 2024 in “Frontiers in Public Health” In this study, researchers developed and tested an Italian version of the Skindex-16AA to assess Health-Related Quality of Life in patients with moderate-to-severe Alopecia Areata, emphasizing the importance of patient perception in evaluating their mental health and quality of life.
23 citations
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August 2022 in “JAMA Dermatology” In this study, patients with alopecia areata indicated a preference for shared decision-making (SDM) with their dermatologists, and those who engaged in SDM reported less decisional regret about their treatment choices.
11 citations
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November 2022 in “JAMA dermatology” This review suggests that certain nutritional supplements may have a potential role in improving hair loss, though evidence quality varies, and such treatments should be discussed collaboratively between physicians and patients.