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Melatonin applied to the scalp helps treat early-stage hair loss in men and women.

Male pattern baldness is not a risk factor for heart disease based on cholesterol levels alone.

Most Cochrane Skin Group reviews are helpful for improving dermatology practices, but some lack enough evidence for clinical recommendations.

The document concludes that there have been significant improvements in diagnosing and treating skin diseases, including melanoma, with new techniques and therapies.

More research is needed to confirm if laser therapy effectively treats hair loss.

Popliteal Artery Entrapment Syndrome (PAES) is a rare but possible cause of leg pain during walking, even in untrained women.

The SGAP flap effectively treats large sacral pressure sores with good results and minimal complications.

Hair transplant surgeries can be improved by preserving follicles in a special solution, and surgeries done at outpatient facilities are more profitable than those at hospitals.

Outpatient aesthetic and reconstructive surgeries are about equally profitable in Academic Health Centers and Ambulatory Surgery Centers when time is considered, but dedicated surgery centers are generally more profitable.

The document reports unique growth lines in a child after Stevens-Johnson syndrome, skin reaction from parsnips and sun in a girl, and itchy skin with xanthomas in a boy with Alagille syndrome.

The document corrects a mistake by stating that pimecrolimus, not tacrolimus, is the drug that concentrates in the skin.

Small injections of dutasteride improved hair thickness in men with hair loss without major side effects.

Physalis peruviana extract is more effective in treating benign prostatic hyperplasia in rats than finasteride and terazosine.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Finasteride reduces urinary issues and surgery need in men with enlarged prostates by over 50%.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Polycystic ovary syndrome affects about 6-10% of women, with varying symptoms and the need for standardized global definitions.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

PCOS affects a similar percentage of Black and White women in the Southeastern United States.

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.