88 citations,
August 1998 in “Carcinogenesis” High levels of ODC and a mutant Ha-ras gene cause tumors in mice.
57 citations,
October 1996 in “Dermatologic clinics” HA-MNs with MXD effectively treat hair loss better than topical MXD with fewer side effects.
September 2024 in “Stem Cell Research & Therapy” HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.
13 citations,
December 2001 in “Journal of Investigative Dermatology” Overexpressing ornithine decarboxylase and v-Ha-ras in keratinocytes leads to invasiveness and malignancy.
269 citations,
October 2018 in “International journal of biological macromolecules” Hyaluronic acid is effective for skin rejuvenation and should be a key ingredient in cosmetic products.
118 citations,
May 2015 in “European journal of pharmaceutics and biopharmaceutics” The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.
85 citations,
June 2008 in “Annals of the New York Academy of Sciences” PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.
49 citations,
October 2009 in “Cancer research” Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
42 citations,
January 2017 in “Stem cells international” Adding hyaluronic acid helps create larger artificial hair follicles in the lab.
34 citations,
September 2020 in “Clinical, cosmetic and investigational dermatology” Hyaluronic acid increases collagen synthesis safely, while poly-L-lactic acid may cause complications by affecting fibroblasts.
34 citations,
January 2008 in “International Review of Neurobiology” Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.
26 citations,
March 2017 in “Aesthetic plastic surgery” Accidental injection of hyaluronic acid caused temporary hair loss and skin damage, but treatment restored hair and healed the skin.
24 citations,
March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
20 citations,
June 2014 in “Pharmaceutical research” Using both hyaluronic acid compounds together improves skin hydration and reduces wrinkles better than using one alone.
17 citations,
June 2017 in “Journal of pharmaceutical sciences” Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
15 citations,
February 2015 in “Han-gug chugsan sigpum hag-hoeji/Korean journal for food science of animal resources” Egg shell membrane hydrolysates can reduce wrinkles and improve skin health.
12 citations,
February 2022 in “Acta Biomaterialia” Minoxidil-loaded hyaluronic acid microneedles can effectively increase hair growth and could be a promising treatment for hair loss.
10 citations,
August 2021 in “Cosmetics” The best shampoo formula used 1% high-weight hyaluronic acid, 10% acidic sophorolipid, and 1% salt for effective hair conditioning and cleansing without sulfates or silicones.
8 citations,
February 2005 in “International Journal of Cosmetic Science” Applying a special soy milk extract on skin can make it more elastic and hydrated.
7 citations,
January 2015 in “Evidence-based Complementary and Alternative Medicine” The review suggests renaming two herbs to avoid confusion and recommends more research for safe use.
6 citations,
January 2018 in “Annals of dermatology/Annals of Dermatology” Hyaluronic acid filler can safely and effectively improve facial contour in Parry-Romberg Syndrome.
5 citations,
October 2021 in “BioMed Research International” Noncrosslinked hyaluronic acid helps human hair cells grow and could be a potential hair loss treatment.
5 citations,
October 2018 in “Journal of Clinical Laboratory Analysis” Women with PCOS who have high male hormone levels often also have insulin resistance.
5 citations,
April 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” AMH levels can't reliably tell the difference between LOCAH and all types of PCOS in women with excessive hair growth.
4 citations,
October 2022 in “Aesthetic surgery journal” Injecting hyaluronidase into the artery is effective for treating skin death and hair loss caused by hyaluronic acid fillers.
3 citations,
July 2023 in “International Journal of Biological Macromolecules” The hydrogel helps heal wounds and regrow hair by mimicking a baby's environment.
3 citations,
September 2018 in “Journal of Biomaterials Science, Polymer Edition” Different materials affect the growth of brain cells and fibroblasts, with matrigel being best for brain cell growth.
2 citations,
March 2021 in “Pakistan veterinary journal” Hyaluronic acid filler injections can quickly and effectively treat canine entropion for 6-8 months without surgery.
2 citations,
January 2019 in “Biomecánica” Hyaluronic acid and versican are important for skin healing and hair growth and might help in regenerative medicine.