57 citations
,
December 1960 in “Archives of Dermatology” This introduction reviews historical use of steroids for alopecia treatment, mentioning early cases of hair regrowth with cortisone acetate but provides no new clinical data.
56 citations
,
September 2013 in “Journal of Biochemistry and Molecular Biology” This study observed that androgen treatment increased ROS production and TGF-β1 secretion in rat hair follicle dermal papilla cells, suggesting that the androgen-induced TGF-β1 is mediated by ROS.
56 citations
,
May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
56 citations
,
June 2015 in “Nature Protocols” This protocol describes using two-photon laser-scanning microscopy to study hair regeneration in live mice, offering detailed imaging capabilities for observing hair follicle stem cell behavior and manipulating cellular populations.
56 citations
,
March 2015 in “Journal of Investigative Dermatology” Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
56 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that the susceptibility of hair follicle melanocytes to oxidative stress as they age may be key in the graying of hair due to reduced catalase expression and activity.
56 citations
,
November 2010 in “Pigment Cell & Melanoma Research” This article discusses the role of neurohormones and neuropeptides in hair follicle pigmentation and outlines promising neuroendocrinological strategies to address greying and damage, but reports no new clinical results.
56 citations
,
June 2010 in “Clinical and experimental dermatology” In this study, coudability hairs were identified as a useful marker for assessing disease activity in patients with alopecia areata and may serve as an alternative to the hair-pull test.
56 citations
,
February 2006 in “American journal of physiology. Cell physiology” This study observed that in hormone-starved prostate cancer cells, the androgen 5alpha-dihydrotestosterone rapidly induces matriptase activation and shedding, which involves androgen receptor signaling and requires both transcription and protein synthesis.
56 citations
,
July 2005 in “Experimental Dermatology” This study demonstrated that hair follicle-derived cells can induce hair follicle formation in an in vitro skin organ culture system using human retroauricular skin specimens.
56 citations
,
June 2002 in “Biomaterials” This study found that controlled release of VEGF via a collagen hydrogel promoted hair follicle growth and cell proliferation in mice more effectively than free VEGF injections.
56 citations
,
July 2001 in “International Journal of Clinical Pharmacology and Therapeutics” This article reviews the psychodynamic factors and treatment options for dysmorphophobia, highlighting the need for intensive psychotherapy, and introduces the concept of "Dorian Gray Syndrome.
56 citations
,
January 2001 in “Dermatology” This study introduces the concept of teloptosis, which influences hair shedding during the telogen phase and affects hair density, highlighting that early or delayed teloptosis has noticeable effects.
56 citations
,
January 1996 in “Journal of Forensic Sciences” This study found that rhodamine B penetrated human hair fibers more effectively from an aqueous solution compared to a methanol/ethanol solvent, with penetration depending on hair morphology.
56 citations
,
August 1994 in “PubMed” This study found that prolactin and melatonin both stimulated hair shaft elongation in Cashmere goat hair follicles, with maximum growth observed at specific concentrations, although melatonin reduced follicle viability after 96 hours.
56 citations
,
December 1990 in “Differentiation” Growth factors can either promote or inhibit hair follicle cell growth and collagen breakdown.
55 citations
,
September 2017 in “Journal of Cosmetic Dermatology” This review discusses the diverse applications of platelet-rich plasma in aesthetic dermatology and assesses the existing literature on its effectiveness, reporting no new clinical results.
55 citations
,
January 2016 in “Annals of Dermatology” This study found that repeated microneedle stimulation in mice promoted hair growth and increased the expression of hair-growth-related genes, suggesting potential therapeutic uses for alopecia.
55 citations
,
May 2017 in “Current stem cell research & therapy” In this study, Japanese patients treated with adipose-derived stem cell-conditioned medium for hair regeneration showed positive outcomes, suggesting it may be an effective new therapy for alopecia.
55 citations
,
April 2017 in “Experimental Dermatology” This article details laboratory methods for isolating and culturing human dermal papilla cells but provides no new experimental results.
55 citations
,
April 2015 in “BMC medicine” This study found that the Stem Cell Educator therapy improved hair regrowth and quality of life in patients with severe alopecia areata by restoring immune balance and protecting hair follicles from autoimmune damage.
55 citations
,
November 2010 in “Development” This study observed that in frizzled 6 null mice, initially uncorrelated hair follicle orientations develop into highly ordered patterns over time, suggesting possible mechanisms for biological structure patterning.
55 citations
,
March 2010 in “Aging” This study found that circadian clock genes are involved in regulating the hair growth cycle, suggesting a connection between daily rhythms and the longer hair follicle cycling process.
55 citations
,
October 2008 in “American Journal Of Pathology” mIGF-1 in skin cells speeds up wound healing and hair growth in mice without harmful effects.
55 citations
,
March 2007 in “Journal of cosmetic dermatology” This review discusses the historical development of hair straightening products for Afro-ethnic hair and reports no new research findings.
55 citations
,
January 2004 in “The International Journal of Developmental Biology” This study reports that corneal transient amplifying cells can be reprogrammed into epidermal cells capable of forming hair follicles in response to embryonic dermis signals.
55 citations
,
October 2003 in “Dermatologic Clinics” This article discusses the complexities of treating hair and scalp disorders in African American patients, emphasizing the importance of understanding their specific hair care practices and the unique impact on quality of life, but reports no new empirical findings.
55 citations
,
May 1995 in “The journal of investigative dermatology/Journal of investigative dermatology”
55 citations
,
October 1992 in “Archives of Dermatology” In this study, researchers observed that loose anagen hair syndrome is an autosomal dominant disorder characterized by abnormal hair follicle structure and premature keratinization, possibly due to signaling and desmosomal component disturbances.
55 citations
,
June 1987 in “PubMed” In this study, cyclosporin A treatment significantly increased hair length in nude mice compared to controls, but hair growth reversed after treatment stopped.