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Enzymes called PADIs play a key role in hair growth and loss.

Epigenetic changes in blood cells may contribute to alopecia areata.

Inhibiting class I HDACs helps maintain hair growth ability in skin cells.

Trichostatin A helps restore hair-growing ability in skin cells used for hair regeneration.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

Histone modification is key in treating chronic inflammatory skin diseases.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.

Hair growth genes work better with more glucose due to changes in gene-regulating markers.

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

MOF controls skin development by regulating genes for mitochondria and cilia.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.