Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review presents clinical and preclinical evidence supporting innovative regenerative approaches to treat vitiligo, as existing treatments lack a specific cure and predictable long-term repigmentation outcomes.

This study found that multi-walled carbon nanotubes promoted root hair growth in certain plants, with results indicating they modulate nitric oxide and ethylene pathways crucial to this development.

This study found that GhPLDα1 in upland cotton may be involved in fiber development, correlating with increased hydrogen peroxide and cellulose biosynthesis during secondary cell wall thickening.

This review highlights the rapid advancements in 3D bioprinting techniques, emphasizing their role in enhancing regenerative therapy, drug delivery, and bioengineering applications while addressing current challenges in bioink formulation and bioprinting stability.

This review discusses nitric oxide's physiological roles and the development of strategies for delivering it exogenously, without presenting new clinical results.

Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.

This review discusses how functionalized hydrogels can modulate the microbiome to aid tissue regeneration and infection control, highlighting their potential to deliver therapeutic agents effectively and support beneficial immune responses.

This review discusses the benefits of β-sitosterol, a plant compound found in nuts and seeds, which may lower "bad" cholesterol and help prevent heart disease, cancer, and diabetes, but notes the lack of clinical studies on its safety and effectiveness in humans.

This study found that erythrocyte-anchored CPA-encapsulated nanoparticles improved the delivery and accumulation of Cepharanthine in the lungs, enhancing its effectiveness in treating acute lung injury by reducing inflammatory responses.

This study found that in estrogen receptor-positive breast cancer cells, 17β-estradiol repressed polyamine oxidase transcription by interacting with AP-1 sites on its promoter.

This study found that PEGylated Ag₂S-ZnS@TGA-AA heteronanostructures, activated by light exposure, showed synergistic antibacterial effects against multidrug-resistant bacteria, significantly accelerating the healing of MRSA-infected wounds in comparison to untreated wounds.

This review discusses the role of extracellular vesicles as therapeutic agents for wound healing and highlights the need for further research into their clinical applications.

This review discusses the potential of adipose-derived stem cell extracellular vesicles (ADSC-EVs) in skin regeneration, highlighting mechanisms like inflammation and angiogenesis, but reports no new clinical results; challenges and future prospects are also considered.

This article discusses the potential of novel microneedle transdermal systems for enhanced drug and vaccine delivery through the skin, but reports no clinical results and emphasizes ongoing trials.

This review examines adipose-derived stem cells as a promising therapy for alopecia but reports no new clinical results, discussing their potential mechanisms and the challenges faced in treatment development.

This review compiles existing research on ischemia-modified albumin (IMA) as a biomarker for myocardial ischemia, highlighting current gaps in understanding its formation and detection, with no new clinical results reported.

Bhamrung-Lohit may help with inflammation and oxidation.

This study's literature synthesis suggests that silymarin, derived from milk thistle, may offer protective benefits for the skin, including defense against UV damage and support for wound healing, though further clinical studies are needed.

This review analyzed current studies on metabolite production from the medicinal fungus Cordyceps militaris, focusing on its fermentation modes and biological functions, and emphasizes the need for modern fermentation processes to enhance industrial production.

In this study, researchers developed a composite paste system using minoxidil-loaded nanoparticles and valproic acid, enhanced by roller-microneedles, which significantly stimulated hair regeneration and perifollicular vascularization in an androgenetic alopecia mouse model, reducing side effects compared to traditional treatments.

This review highlights that a comprehensive approach combining pharmacological, immunomodulatory, and regenerative interventions, including phototherapy enhanced with topical treatments and JAK inhibitors, appears effective and promising in the management of vitiligo by addressing its autoimmune and melanocyte-loss aspects.

This review reports that resveratrol could benefit the management of chronic illnesses such as diabetes and cardiovascular disease, but challenges with bioavailability and regulatory issues persist.

This study developed a hydrogel microneedle system combining ginseng-derived exosomes and biomimetic nanoparticles to address oxidative stress, inflammation, and melanocyte deficiency in vitiligo, showing significant repigmentation in mice within 3 weeks by enhancing melanocyte protection and keratinocyte proliferation.

This systematic review synthesizes evidence from the past 20 years to highlight the potential of exosome-based therapies from stem cells and plants in improving cutaneous repair, skin aging, and challenging dermatological conditions through mechanisms like immunomodulation and collagen remodeling.

In this systematic review, animal studies showed that cytarabine causes multi-organ toxicities, notably neurotoxicity, linked to oxidative stress and other mechanisms, though study quality raises concerns about reliability and translation to human outcomes.

This review highlights the application of microneedle technology as a promising advancement in psoriasis management, focusing on its roles in enhanced transdermal drug delivery and minimally invasive biomarker monitoring, while also discussing current challenges and future research directions.

This study involving 81 yaks found significant correlations between melatonin, dihydrotestosterone, and immunoglobulin levels in blood serum and mineral content in hair, suggesting these factors may jointly influence yak hair growth and immune status, providing a potential non-invasive indicator of overall health.

This study developed a novel hair-straightening shampoo incorporating a polyphenol–inorganic sulfate redox agent, finding that it effectively straightens hair while enhancing strength and reducing damage due to its protective polyphenol coating.

This study suggests that hemoglobin α expression in the epidermis is induced by oxidative stress and may function as an antioxidant, contributing to skin barrier function.

In this study, Iris germanica L. rhizome-derived exosomes were found to reduce oxidative stress, enhance antioxidant enzyme transcription, and restore cellular function in human epidermal keratinocytes, suggesting potential protective effects against oxidative-stress-induced skin damage.