November 2023 in “ACS Applied Polymer Materials” In this study, the researchers developed a new method using H2O2/TiO2/UV for extracting human hair keratins rapidly, yielding higher protein and enabling the production of keratin films with better hemostatic performance and varied wound-healing properties compared to films from traditionally extracted keratin.
1 citations
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September 2018 in “International journal of research - granthaalayah” This paper introduces a new understanding that the human hair follicle medulla lacks metabolic activity for H2O2 breakdown, indicating that H2O2 decomposition occurs primarily in the cortical areas.
1 citations
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September 2025 in “Molecules” This study comparatively evaluated different extraction techniques for Schinus terebinthifolius Raddi leaf extracts and found that conventional extraction with ethanol yielded the highest antioxidant activity and beneficial effects on skin cell viability, supporting its potential use in sustainable cosmeceutical formulations targeting skin aging.
2 citations
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January 2023 in “Frontiers in Oncology” In this rat study, subcutaneous injections of hydrogen peroxide and cumene hydroperoxide appeared to completely prevent chemotherapy-induced hair loss by inducing cell cycle arrest, suggesting a novel approach to help cancer patients maintain their quality of life during treatment.
305 citations
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July 2016 in “International Journal of Biological Macromolecules” This review describes the roles of polysaccharides in antitumor, antiviral, and anti-inflammatory activities and introduces methods for their isolation and purification, reporting no new research results.
4 citations
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March 2019 in “Acta Chromatographica” This study developed two sensitive chromatographic methods for determining finasteride and tamsulosin hydrochloride in pharmaceutical forms, validated against International Conference on Harmonisation guidelines.
1 citations
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January 2017 in “Asian Journal of Chemistry” New method effectively analyzes finasteride and its stability.
5 citations
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February 2013 in “Journal of Liquid Chromatography & Related Technologies” This study developed and validated a micellar electrokinetic chromatography method to determine finasteride stability, finding that the drug degrades under acidic, basic, and oxidative stress conditions.
46 citations
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January 2009 in “Textile Research Journal” This study presents a DNA-analytical method that can reliably identify and differentiate cashmere, fine wool, yak, and camel hair fibers in both untreated and processed samples.
19 citations
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December 2002 in “Journal of Liquid Chromatography & Related Technologies” This study developed and validated a high-performance liquid chromatographic method for identifying finasteride and its degradation products, showing excellent resolution and sensitivity under various decomposition conditions.
July 2024 in “Medical alphabet” This review article explores the pathogenesis of vitiligo and examines various therapeutic approaches, specifically highlighting the potential use of oral and topical Janus kinase inhibitors for treatment.
April 2018 in “Journal of Chromatographic Science” In this study, researchers found that finasteride undergoes second-order alkaline degradation kinetics and that its degraded form negatively impacts cell proliferation, highlighting the need for careful handling in pharmaceutical manufacturing and storage.
5 citations
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January 2014 in “Asian Journal of Chemistry” This study developed a simple and cost-effective chromatographic method for simultaneously analyzing betamethasone dipropionate and calcipotriol, achieving rapid separation within 7 minutes suitable for routine applications.
4 citations
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November 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study found that a hydro-alcoholic extract of Roselle petals may reduce free radical production during UV-induced photodecomposition of antibiotics, potentially offering protective benefits for patients using similar topical antibiotics.
25 citations
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July 2019 in “Journal of drug delivery science and technology” This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.
16 citations
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March 2008 in “Dermatologic Surgery” This review discusses the effects of hydrogen peroxide in clinical settings, highlighting a lack of data specifically for its use in hair transplant surgery and recommending further research.
4 citations
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December 2007 in “Dermatologic Surgery” This study found that using 3% hydrogen peroxide for surgical wound care during hair restoration did not significantly affect the survival rate of hair grafts compared to normal saline.
April 2026 in “Tissue Engineering and Regenerative Medicine” This study found that the GPRC6A-Duox1 signaling pathway influences hair cycle progression and testosterone-mediated hair loss in mice, suggesting that disruption of this pathway leads to resistance against testosterone-induced hair loss and longer anagen phase duration.
June 2008 in “Dermatologic Surgery” This review discusses the effects of hydrogen peroxide in hair restoration surgery and other medical specialties, finding both potential benefits and risks, but reports no conclusive data for its optimal use in hair transplants.
34 citations
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January 2012 in “Journal of Dermatological Science” In this mouse study, researchers found that hydrogen peroxide and monoethanolamine in hair dyes may be key contributors to dermatitis and hair loss due to oxidative stress.
1 citations
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May 2018 in “International Journal of Molecular Biology Open Access” This manuscript suggests that exogenous hydrogen peroxide is a primary risk factor for higher incidence of cutaneous melanoma in swimmers, with UV radiation playing a secondary role.
February 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, all-trans retinoic acid was found to protect against oxidative stress-induced apoptosis in cultured hair cell-like cells.
This study found that oxidative stress markers, specifically MDA and H2O2, along with decreased SOD activity, may play a key role in the development of diffuse hair loss in the studied population.
84 citations
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February 2013 in “Clinica chimica acta” This review presents evidence that correlations exist between hair mineral imbalances and various diseases, though inconsistencies in results highlight the need for standardized preparation methods.
41 citations
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September 2005 in “Wound Repair and Regeneration” This study found that hydrogen peroxide interfered with scarless healing in a murine fetal wound repair model, potentially by inducing transforming growth factor-beta1, which may contribute to increased fibrosis.
36 citations
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November 2018 in “BMC plant biology” This study suggests that ROXYs and reactive oxygen species are likely involved in the signaling pathways plants use to respond to nitrate deprivation.
25 citations
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September 2014 in “Biological Research” This study found that arctiin, a compound from Arctium lappa, demonstrated protective effects against oxidative stress-induced dysfunction in human hair dermal papilla cells, suggesting potential therapeutic use for alopecia.
12 citations
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December 2017 in “Journal of biomaterials science. Polymer ed.” This study found that protein extracts from human hair demonstrated significant antioxidant abilities, protecting human dermal fibroblasts from oxidative stress, suggesting potential for biomedical applications.
12 citations
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December 2017 in “Food and chemical toxicology” This study found that mixtures used in permanent hair dyes had irritant effects on reconstructed human epidermis, while individual ingredients alone did not.
12 citations
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April 2014 in “Molecular Medicine Reports” In this study, transcriptome analysis identified 68 differentially expressed miRNAs in human dermal papilla cells treated with hydrogen peroxide, suggesting they play a significant role in growth arrest and apoptosis.