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This preclinical study found that finasteride withdrawal in rats caused inflammation in the gut and hypothalamus, while allopregnanolone treatment partially reduced these effects, suggesting potential therapeutic benefits for post-finasteride syndrome.

This review highlights the role of the brain–gut–skin axis in systemic inflammatory skin conditions, revealing potential interventions like microbiome-directed treatments and integrative therapies, though emphasizes the need for more robust clinical validation.

This study found that in male rats, chronic finasteride treatment reduced allopregnanolone levels, which, upon drug withdrawal, correlated with increased pro-inflammatory cytokines and altered neurotransmitter levels.

This case report highlights the challenges of misdiagnosis in women with PCOS and emphasizes the importance of a holistic approach to address interconnected endocrine and reproductive dysfunctions.

This study identified overlapping genetic susceptibility loci in both alopecia areata and inflammatory bowel disease, specifically with Crohn's disease and ulcerative colitis.

This study suggests that cedrol may improve mitochondrial function, gut microbiota, and intestinal barrier integrity, indicating its potential value in treating inflammatory bowel disease.

This review discusses how modern lifestyle factors affecting gut health may contribute to Alopecia Areata in genetically predisposed individuals, reporting no new results but suggesting the need for long-term interventions.

This review reveals that PCOS is consistently linked to gut microbiota dysbiosis, characterized by reduced microbial diversity and shifts in composition, which are associated with various PCOS phenotypes and may present opportunities for microbiota-targeted therapies addressing the disorder's underlying pathophysiological mechanisms.

This study observed that Poria cocos polysaccharides and finasteride both reduced inflammation in chronic nonbacterial prostatitis in rats, but only Poria cocos polysaccharides reversed related changes in the gut microbiota.

This review article proposes a possible skin-gut-fibrosis axis, suggesting that gut microbial metabolites may influence the development of keloids and hypertrophic scars by affecting immune responses and fibrotic signaling pathways, although direct evidence in skin fibrosis remains limited.

This review discusses the complex mechanisms behind acne vulgaris and suggests that dietary modification, along with pro- and prebiotics, may influence its pathogenesis by addressing stress-induced skin inflammation.

This systematic review reported that probiotics, prebiotics, synbiotics, postbiotics, and dietary supplements may improve hair density and reduce dandruff severity in individuals with scalp disorders, potentially by modifying inflammation, oxidative stress, and microbiota composition; however, variability across studies limits the strength of these conclusions.

This study found significant alterations in the scalp and gut microbiome of patients with alopecia areata compared to healthy controls, suggesting a potential link to systemic inflammation and autoimmune response.

This research identified unique gut microbiota patterns in alopecia areata patients, with potential as diagnostic biomarkers and suggesting avenues for microbiota-focused therapies.

This study introduces the concept of a "gut–brain–skin axis" where ingesting a specific Lactobacillus strain in mice may reduce stress-induced skin inflammation and hair growth inhibition.

This review discusses recent research on the relationship between gut microflora and depression, highlighting the potential for new insights into the pathogenesis and treatment of major depressive disorder.

This review discusses the gut-brain-skin axis and its role in skin diseases, advocating for treatments that integrate gut microbiota, mental health, and dietary interventions, but reports no new clinical results.

This review found that microbiota-targeted interventions, particularly certain strains of probiotics, are associated with improvements in skin conditions, most notably in pediatric atopic dermatitis, but their efficacy varies across other dermatological diseases.

This systematic review found that exosomes and gut microbiota play a significant role in skin regenerative processes, suggesting that gut health is crucial for maintaining aesthetically healthy skin, and probiotic treatments may support traditional dermatological therapies for inflammatory skin diseases.

In this study conducted in female mice, maternal Faecalibacterium pathobionts combined with a low-fiber diet increased systemic inflammation and skin problems in offspring, suggesting a link to atopic dermatitis and the influence of dietary trends on chronic conditions.

This review discusses the range of long-term complications, including mucocutaneous, ocular, and psychological sequelae, for survivors of Stevens–Johnson syndrome and toxic epidermal necrolysis, but reports no new clinical results.

This study concluded that Aloe vera fermentation significantly accelerates burn injury healing in rats by reducing inflammation and altering gut microbiota composition.

This review discusses the recent progress in understanding the role of m6A modifications in the development of polycystic ovary syndrome and reports no new clinical findings.

This review discusses the potential benefits of millets for managing Polycystic Ovary Syndrome by improving glycemic control and insulin sensitivity, but reports no new clinical results.

This review discusses the relationship between gut microbiota and polycystic ovarian syndrome (PCOS), including its potential mechanisms and the role of alterations in microbiome composition on PCOS pathophysiology.

This review discusses the roles and therapeutic effects of GLP-1 receptor agonists on the nervous, cardiovascular, and endocrine systems, but reports no new clinical results, emphasizing the need for further research on their impact on metabolism and tumor relationships in type 2 diabetes patients.

Genetics, hormones, and microbiome changes contribute to hidradenitis suppurativa.

This review highlights that gut dysbiosis and bacterial extracellular vesicles are key factors in PCOS pathophysiology, and suggests AI-driven analysis of these profiles could enhance diagnostic accuracy and treatment personalization, though ethical concerns like data privacy and bias must be considered.

This study found that combined dietary supplementation of sodium hyaluronate and eggshell membrane was associated with various improvements in skin and coat health markers in healthy Ragdoll cats.

This review provides a comprehensive synthesis of skin aging research, highlighting the interplay of genetic and environmental factors, cellular mechanisms, and advances in diagnostic and therapeutic strategies, while also addressing current debates and future directions in the anti-aging field.