Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses potential causes and diagnostic tools for alopecia in guinea pigs and highlights the need to evaluate diet and housing, but it reports no original findings.

Guinea pigs' skin issues in the lumbar area may be caused by dermatological problems and need proper care.

This research observed that hairless guinea pig dermal fibroblasts were more sensitive to a toxic exposure than human dermal fibroblasts, suggesting that guinea pigs might serve as an intermediate model for translating in vitro findings to whole organisms.

This study describes the characteristics and potential research applications of the first hairless guinea pigs in Iran, noting their suitability for allergy, dermal, transplantation, and immunology studies.

This study found that codeine incorporation in guinea pig hair varied with pigmentation and was highest in black hair, suggesting the role of eumelanins in drug binding.

This study found that vitamin A dissolved in alcohol penetrates skin quickly and does not impair hair growth, even in large doses, but it does not retard keratinization unlike when dissolved in fatty acids.

In a guinea pig model of dermatophytosis, this study found that subcutaneous CD101, dosed once weekly, demonstrated significant clinical and mycological efficacy compared to the vehicle control and the oral antifungal terbinafine, suggesting potential for CD101 in treating fungal skin infections.

This study found that guinea pig α-lactalbumin transgene was expressed in the mammary glands and sebaceous glands of transgenic mice, with milk protein production occurring in the expected secretory acini.

This study found that a unique transglutaminase in guinea pig hair-follicles, distinct from liver transglutaminase, likely plays a role in forming protein cross-links via ε(γ-glutamyl)lysine bonds.

This study characterized proteins in hair-follicle and hair tissue, identifying similar protein types but with notable quantitative differences, which may reveal aspects of keratin protein synthesis.

This study found that while the combination of oral propranolol and intradermal injections in guinea pigs led to psoriasiform changes, it did not fully mimic psoriasis.

This study observed that reduced in utero exposure to the neurosteroid allopregnanolone increased anxiety-like behavior in female guinea pigs during the juvenile period without affecting long-term allopregnanolone levels.

This case report documents a 3-year-old guinea pig with hormonally active ovarian cysts, cystic endometrial hyperplasia, and bacterial endometritis associated with a uterine foreign body.

In this study, itraconazole was shown to accumulate in the deeper skin layers of guinea pigs after oral administration, suggesting this delivery method effectively targets infective organisms there.

In this study, researchers found that a single oral dose of afoxolaner was safe and effective in treating a severe case of Trixacarus caviae mange in a guinea pig, achieving full remission of clinical signs and mite eradication within 4 weeks without needing repeated treatment.

This case report describes two guinea pigs infested with Acarus farris mites, which were successfully treated with Phoxim and removal of contaminated hay, leading to rapid resolution of skin lesions and alopecia.

In a laboratory study on guinea pigs, Kepok banana peel extract serum at a 30% concentration showed promising effectiveness for hair growth, with results close to those of 5% minoxidil®, suggesting it could be a viable hair care alternative.

This study found that using a non-invasive multielectrode array for gene electrotransfer in hairless guinea pigs increased gene expression in the epidermis significantly, with minimal skin changes observed.

In this study, gamma benzene hexachloride washes successfully resolved skin disease in guinea pigs affected by Trixacarus caviae, after confirmation via skin scrapings.

This case report describes a sarcoptic mange outbreak caused by Trixacarus caviae in a guinea pig breeding colony, which was successfully treated with subcutaneous ivermectin injections and preventive spraying.

This study found that adapalene-loaded microemulsions significantly enhanced the drug's penetration through guinea pig skin compared to an aqueous suspension, with factors like surfactant ratios and the water-oil phase balance affecting the transfollicular drug delivery efficiency.

This study found that adipose-derived stem cells from adult guinea pigs can differentiate into hair cell-like cells in vitro, suggesting potential use in tissue engineering.

This study found that mycophenolate mofetil can enhance skin pigmentation in vitiligo models by activating the WNT signaling pathway and increasing melanin-related gene expression.

This study found that applying a surfactant solution with 2.5% selenium disulfide to the back of guinea pigs significantly increased telogen hair, which may relate to observations of diffuse hair loss in humans under intense exposure conditions.

This study found that different diets had a negligible impact on guinea pigs' hair structure and did not significantly alter their health parameters, suggesting both tested diets met their nutritional needs without affecting their well-being.

This study found that type III collagen was significantly more abundant in the recovering traumatic skin of guinea pigs compared to normal skin, indicating it may play a role in tissue repair.

This study found that decreased allopregnanolone levels through inhibition or intrauterine growth restriction in guinea pigs were linked to altered brain development markers, suggesting a role for neurosteroids in fetal brain protection and development.