This study reports that Hair RiseTM microemulsion, made from plant extracts, significantly enhanced hair follicle cell growth and improved hair growth signaling pathways, suggesting it as a plant-based alternative for androgenetic alopecia treatment.
54 citations
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June 2023 in “International Journal of Molecular Sciences” This review reports that myricetin, a naturally occurring antioxidant in plants, may assist in cancer management by enhancing the effects of existing drugs and inhibiting inflammatory markers, based on in vivo and in vitro studies.
24 citations
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March 2020 in “Cells” This review provides an overview of natural product-derived small molecule modulators of the Wnt signaling pathway, exploring their potential as therapeutic agents for tissue regeneration and cancer treatment.
22 citations
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April 2021 in “Human Cell” MicroRNAs may help diagnose and treat hair loss disorders.
11 citations
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October 2020 in “PLoS ONE” This study found that scalp cooling markedly reduces cellular uptake of anthracycline drugs in human keratinocytes, partially explaining its protective effect against chemotherapy-induced cytotoxicity.
8 citations
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February 2022 in “Molecules” This study found that Asparagus racemosus root extract significantly reduced facial sebum production and pore size in male volunteers, suggesting potential application as an anti-sebum ingredient in cosmetics.
7 citations
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January 2017 in “Clinical and medical investigations” This paper reviews the historical use and contemporary relevance of plant-derived cosmetics, focusing on Suriname's herbal cosmetics industry and the potential to establish a beauty products industry there, without presenting new findings.
6 citations
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October 2023 in “Pharmaceuticals” This study found that the extract of Eclipta prostrata L. demonstrated high antioxidant and anti-acetylcholinesterase activities, moderate inhibition of enzymes linked to diabetes, and favorable ADMET properties, suggesting potential cognitive and diabetes management benefits.
4 citations
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April 2021 in “Majalah Farmasetika” This review discusses formulations and evaluation of herbal shampoos for hair growth stimulation, finding licorice extract shampoo to be the most effective, and reports no new clinical results.
4 citations
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December 2017 in “PubMed” This study observed that minoxidil significantly downregulated 5α-R2 gene expression in human keratinocyte cells, suggesting an antiandrogenic mechanism of action in alopecia.
2 citations
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May 2025 in “Frontiers in Immunology” This study explores the regulatory effects of ursolic acid on macrophage function and suggests potential for developing new anti-inflammatory and immunomodulatory drugs, though further research is needed for clinical applications.
1 citations
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February 2023 in “Plants” This study reported that rice bran oil from the Thai rice variety BB4CMU showed potential in promoting melanin production and inhibiting steroid 5α-reductase, suggesting a natural option for hair revitalization.
December 2025 in “Phytomedicine Plus” This review summarizes recent advances in alopecia management, focusing on combining synthetic and herbal therapies with innovative drug delivery systems like nanocarriers to enhance effectiveness and reduce side effects, while noting challenges with skin penetration and bioavailability.
January 2025 in “Pharmaceuticals” This review discusses the role of nanocarrier systems, such as nanoemulsions and liposomes, in delivering antioxidants into the skin to counteract oxidative stress, highlighting recent advancements in topical antioxidant therapy through nanotechnology.
January 2024 in “Pharmacy information” New treatments using stem cells and other methods show promise for promoting hair growth in androgenetic alopecia.
In this study, the SFE-4 extract from coffee pulp demonstrated potential effects for treating androgenetic alopecia by enhancing cell proliferation and gene expression related to hair growth pathways in vitro, using human hair follicle dermal papilla and prostate cancer cells.
May 2023 in “Journal of Ethnopharmacology” In this study, Allium macrostemon Bunge extract was found to promote hair regrowth in a testosterone-induced androgenetic alopecia mouse model by activating Wnt/β-catenin signaling and boosting hair dermal papilla cell proliferation and growth factor expression.
September 2021 in “IP Indian Journal of Clinical and Experimental Dermatology” In this study, Diabliss Hair Water was found to improve hair growth rate, density, and quality while reducing hair fall in healthy adults experiencing hair thinning concerns.
December 2024 in “Nutrients” In this review, skin changes like hair loss and brittle nails linked to nutritional deficiencies common in eating disorders are examined as critical diagnostic tools, highlighting the need for integrated care involving dermatologists, psychiatrists, and nutritionists for effective management.
205 citations
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September 2018 in “Nutrients” This review summarizes the volatile components, biological activities, and potential safety concerns of essential oils from various Curcuma species, but reports no new clinical results.
57 citations
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May 2021 in “Molecules” This review explores the chemical composition and biological activities of essential oils from selected aromatic roots, highlighting their potential for various industries, though more research is needed to standardize their bioactive components.
49 citations
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October 2022 in “PubMed” This review examines alopecia, its causes, the impact of micronutrients, and the role of the Mediterranean diet, noting conflicting data and a need for more research on diet's effect on hair loss.
7 citations
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January 2022 in “Scientific Reports” This study found that Acanthus ebracteatus extract and verbascoside induced dermal papilla cell proliferation and reduced inflammatory cytokine release in vitro, suggesting potential for anti-hair loss applications.
January 2026 in “Magazine Portal Bibliotech Digital (Universidad Nacional de Colombia)” This study found that rosemary extracts, both individually and in combination as shampoo and hair tonic, stimulated significant hair growth in male C57BL6//BIOU mice, even surpassing the growth achieved with the commercial drug 5% minoxidil.
June 2024 in “Molecules/Molecules online/Molecules annual” This study found that Platycladus orientalis flavonoids may reduce oxidative damage and slow melanin degradation in AGA-affected hair, improving its quality.
June 2026 in “International Journal of Research Publication and Reviews” This study aimed to develop a herbal anti-dandruff shampoo using guava leaves extract and aloe vera gel, which may be safer and more effective for dandruff treatment than chemical-based alternatives, and evaluated it on various parameters including pH, viscosity, and antifungal activity.
3 citations
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January 2017 in “International journal of research - granthaalayah” In this study, thirty participants applied a paste made from Elaeocarpus serratus and Psidium guajava leaves on their scalps, resulting in significant improvements in dandruff symptoms, with over 40% achieving complete remission and no adverse effects reported.
1 citations
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January 2017 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, the researchers found that a paste made from Elaeocarpus serratus and Psidium guajava leaves significantly reduced dandruff symptoms, with more than 40% of patients experiencing complete remission and 30% showing marked improvement, without any adverse reactions during the one-month treatment period.
August 2026 in “World Journal of Pharmaceutical Research” This study explored the development and evaluation of a tablet-form herbal shampoo formulated with natural ingredients like Shikakai, Reetha, and Amla, which reportedly enhance hair shine, growth, and root strength without side effects, offering an environmentally friendly alternative to conventional shampoos.
August 2026 in “World Journal of Pharmaceutical Research” This study explored the creation and assessment of a tablet-form herbal shampoo made with natural ingredients such as Shikakai, Reetha, and Amla, reportedly improving hair shine, growth, and strength of roots without side effects, offering an eco-friendly alternative to conventional shampoos.