97 citations,
March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
60 citations,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
52 citations,
October 2004 in “Veterinary dermatology” Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.
52 citations,
May 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Parathyroid hormone-related protein helps control hair growth phases in mice.
42 citations,
July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
28 citations,
August 2018 in “BMC genomics” DNA methylation changes are linked to hair growth cycles in goats.
24 citations,
October 2017 in “Scientific reports” Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.
17 citations,
June 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.
15 citations,
July 2008 in “Journal of Dermatological Science” Ephrin-A3 helps increase and speed up hair growth in baby mice.
7 citations,
January 1981 in “Springer eBooks” The document concludes that hair biology is complex and there are still unanswered questions about hair loss and follicle changes.
1 citations,
August 2023 in “Nature communications” Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.
38 citations,
June 2018 in “Plant & cell physiology/Plant and cell physiology” Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.
75 citations,
October 2010 in “Mammalian genome” Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.
60 citations,
August 2008 in “Human molecular genetics online/Human molecular genetics” A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.
46 citations,
January 1991 in “Journal of Investigative Dermatology” Minoxidil works in liver and outer hair root sheath for hair growth.
33 citations,
May 2006 in “Journal of Investigative Dermatology” PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.
8 citations,
March 2019 in “Open Biology” The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
6 citations,
June 2021 in “Developmental biology” Dermal EZH2 controls skin cell development and hair growth in mice.
3 citations,
March 2020 in “International Journal of Molecular Sciences” Thymosin β4 helps increase hair growth in Cashmere goats.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
31 citations,
November 2016 in “Cell Reports” Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
17 citations,
August 2018 in “BMC Genomics” The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.
5 citations,
February 2019 in “PloS one” Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.
1 citations,
September 2015 in “Elsevier eBooks” SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
Hair loss can cause significant social and emotional issues, especially for women and young men.
January 2023 in “Journal of applied animal research” Short photoperiods improve cashmere growth and quality in goats by changing hormone levels and gene expression.
92 citations,
November 2006 in “Proceedings of the National Academy of Sciences of the United States of America” BMP signaling controls hair follicle size and cell growth by affecting cell cycle genes.
81 citations,
September 2009 in “Birth defects research” Different body areas in mice produce different hair types due to interactions between skin layers.
40 citations,
June 2013 in “Scientific Reports” A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.