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This study found that melatonin may enhance hair growth properties in dermal papilla cells by activating the AKT/GSK3β/β-catenin signaling pathway through melatonin receptors.

This study suggests that melatonin may promote hair growth properties by activating the AKT/GSK3β/β-catenin signaling pathway in dermal papilla cells.

This study found that in male mouse pancreatic islet β cells, testosterone enhances glucose-stimulated insulin secretion by being locally converted into dihydrotestosterone and estradiol.

In laboratory models of human skin, this study found that treating with resveratrol significantly increased glutathione levels, potentially enhancing the skin's antioxidant defenses.

This study found that adenosine promotes hair growth by stimulating the Wnt/β-catenin pathway in cultured human dermal papilla cells through activation of the adenosine receptor.

This study found that increased intracellular expression of thymosin β4 is necessary and sufficient to induce PAI-1 gene expression in endothelial cells, potentially mediated through Ku80 as a novel receptor.

In this study, researchers found that the G(S)alpha subunit is strongly expressed in neonatal mouse hair follicles, indicating it may play a role in initiating follicle growth.

This study found that quaternary ammonium iminofullerenes (IFQA) can alleviate oxidative stress in maize caused by hydrogen peroxide, promoting root growth by enhancing antioxidant cycles and reducing ROS accumulation.

Ent-kaurane-type diterpenoids from Isodonis Herba may promote hair growth by boosting cell proliferation.

This study suggests that melatonin promotes hair growth-related properties in DP cells by activating the AKT/GSK3β/β-catenin signaling pathway through melatonin receptors in a 3D spheroid culture system.

This study found that low molecular weight collagen peptide from fish may promote hair growth in both human cells and mice by activating the Wnt/β-catenin signaling pathway.

Water extract of cacumen platycladi helps hair growth by affecting specific cell pathways.

This study found that the water extract of Cacumen Platycladi promotes hair growth and follicle development in mice, possibly by influencing dermal papilla cells through the Akt/GSK3β/β-Catenin signaling pathway.

This study found that ginsenoside Rb1 promoted the growth of mink hair follicles and dermal papilla cells, potentially through activating the PI3K/AKT/GSK-3β signaling pathway.

This study found that GS-KG9 and GS-E3D, bioactive ginseng extracts, reduced BBB disruption and neuronal apoptosis in the hippocampus of diabetic rats, suggesting potential therapeutic effects for diabetic patients.

This research found that escin, when applied topically, enhances blood flow in human skin and promotes changes in endothelial cell signaling pathways, suggesting potential benefits for improving cutaneous microcirculation.

In this study, human dermal fibroblasts were identified as natural host cells that support productive Merkel cell polyomavirus infection, and the MEK antagonist trametinib was introduced as an effective inhibitor to control the virus.

This study concluded that selenium supplementation for ovarian cancer patients during chemotherapy may have several beneficial effects, such as increased antioxidant enzyme activity, reduced chemotherapy-related symptoms, and higher selenium levels in serum and hair.

This study found that androgens inhibit hair follicle stem cell differentiation by disrupting the Wnt signalling pathway in dermal papilla cells, but Wnt activation can restore differentiation.

This study found that valproic acid promoted hair re-growth in C3H mice by activating the Wnt/β-catenin pathway, suggesting its potential as a treatment for alopecia.

This study found that administering melatonin for 12 weeks to women with PCOS significantly reduced hirsutism, testosterone, and inflammation markers, while enhancing antioxidant levels compared to a placebo.

This study demonstrated that dominant mutations in mouse gasdermin A3 disrupt mitochondrial oxidative stress regulation, suggesting a gain-of-function effect on epidermal differentiation.

This review discusses newly identified non-Edg family lysophosphatidic acid receptors, detailing their roles in vascular development, platelet activation, and hair growth, and reports no clinical results.

This review discusses oxidative stress's role in polycystic ovary syndrome and examines various biomarkers to understand its impact on the disorder's pathogenesis, but reports no new clinical results.

This study observed that patients with alopecia had increased lipid peroxidation and decreased antioxidants, including lower beta-carotene, GSH levels, and GSH-Px activity, compared to healthy controls.

This study found that valproic acid promoted human hair growth by increasing β-catenin levels, suggesting it may be a potential therapeutic option for alopecia.

This study reported that reconstructed skin models can be useful for studying the effects of non-water-soluble topical products on xenobiotic metabolism, particularly in enzyme activities like EROD and GST.

This review suggests that skin may largely protect itself from CYP-generated reactive metabolites due to higher conjugating enzyme activities, while highlighting limitations in modeling human skin metabolism experimentally.

In this study, N-WASP deficiency in mouse skin was found to cause severe alopecia and disrupt hair follicle cycling by 5 months, highlighting its critical role in skin function and Wnt signaling.

In this study, Geranium sibiricum L. extract promoted hair growth in vitro with human dermal papilla cells and in vivo in mice, outperforming minoxidil by proliferating cells and stimulating growth factor expression, suggesting its potential as a hair growth treatment.