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This study investigated the association between hair loss and medications affecting the GH/IGF-1 pathway, using the FDA Adverse Event Reporting System to analyze reporting odds ratios of alopecia.

In a murine model of androgenetic alopecia, this study found that the newly designed IGF-1 biomimetic peptide Ac-GFFY-IGF led to faster and superior hair regrowth compared to minoxidil, suggesting potential for improved human therapies.

In this study, a combination of GFM-lotion with autologous PRP treatment improved efficacy in treating androgenic alopecia compared to PRP alone, as shown by significant improvements in clinical assessments over 3 months.

In this study, DHT was found to inhibit hair growth in mice by decreasing IGF-I production in dermal papillae through reduced sensory neuron stimulation.

Eating isoflavone can help mice grow hair by increasing a growth factor.

This study reports that stimulating sensory neurons with capsaicin and isoflavone increases IGF-I production, promoting hair growth in mice and human volunteers with alopecia.

This study found that collagen peptides from Mozambique tilapia significantly promoted hair regrowth and increased the proliferation of hair growth factors in vitro and in vivo, suggesting potential as supplements for hair loss prevention.

This literature review highlights a potential but uncertain link between GLP-1 receptor agonist therapy for type 2 diabetes and obesity and hair loss, with variations among different medications.

This review discusses the role of growth factors in hair physiology and their involvement in conditions like androgynous and focal alopecia, reporting no new clinical findings.

This review discusses various hormonal and neuropeptide influences on hair growth and reports no new clinical results; it highlights complexity and suggests areas for future exploration.

This study suggests that low molecular weight fish collagen peptide may promote hair follicle growth and regeneration, improving overall hair quality in mouse models.

This study reported that the use of composite RGDmix hydrogel improved the survival and proliferation of human amniotic mesenchymal stem cells and increased growth factor expression, enhancing wound healing through the RGDSP/integrin αv/PI3K/AKT signaling pathway.

This study evaluated a novel synthetic cell-penetrating peptide, DualPep-ALO, finding it promotes hair growth by enhancing follicle cell proliferation, activating regenerative pathways, and reducing inflammation and oxidative stress in vitro and ex vivo, suggesting a promising new topical treatment for hair loss that rivals minoxidil.

This study found that a novel peptide, FOL-005, derived from osteopontin, significantly inhibited hair growth in human hair follicles both ex vivo and in vivo, suggesting potential as a treatment for unwanted hair growth.

This study describes commonly used peptides, proteins, and growth factors in cosmeceuticals and discusses their potential benefits in dermatology, though their long-term effects remain unconfirmed.

In this study, researchers developed EPO-derived peptides that enhanced hair growth by stimulating dermal papilla cells and increasing IGF-1 expression without triggering systemic erythropoietic effects in tested models, indicating a promising approach for treating hair loss.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

This review explores the complex endocrine functions of human skin and its role as a peripheral endocrine organ, but reports no new clinical results.

This study identified the osteopontin-derived peptide, FOL-005, as a potential inhibitor of unwanted human hair growth by promoting catagen development without reducing stem cell numbers or showing toxicity.

This study found that inhibiting TGF-β receptors in adult dermal fibroblasts restored their function and increased resistance to Staphylococcus aureus infection by enhancing their adipogenic and antimicrobial capabilities.

This review discusses mechanisms and potential dietary influences on alopecia, proposing molecular targets like TRPVs and endocannabinoids as avenues for treatment but reports no new clinical results.

This study reviews new treatments for androgenetic alopecia, including cell-derived exosomes and investigational drugs, which show potential to improve hair density and quality but require more rigorous and standardized trials to confirm efficacy and safety.

This article reviews the current challenges, innovations, and prospects of cosmetics designed to prevent hair loss and encourage hair growth, highlighting evolving technologies like gene therapy and the need for multidisciplinary approaches.

In this systematic review, researchers found that injectable therapies, including agents like dutasteride and multivitamin formulations, may offer cosmetic benefits for androgenetic alopecia; however, evidence is limited by small study sizes, varied methods, and short follow-up periods, necessitating standardized trials for routine use recommendations.

This study identified neuropilin-1 as the receptor for FOL-026 and showed that it stimulates angiogenesis and cell growth, suggesting potential for vascular repair and enhanced angiogenesis therapies.

This review discusses hormonal influences on hair growth and suggests that understanding hormone-gene interactions may improve treatment of hirsutism and alopecia, but reports no new clinical findings.

Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.

This review discusses the unique features of dermal white adipose tissue, its interaction with hair follicles, and its role in skin physiology, reporting no new experimental findings.

This article discusses the role of clinical observation and microscopic correlation in American dermatology training and reports no new clinical results.

This study highlights keratin biomaterials as a promising biocompatible option for wound healing and tissue regeneration but notes that further clinical studies are necessary to confirm their effectiveness.