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GlossaryAnagen Phase (Growth Phase Hair)

active period of hair growth in the hair cycle

The Anagen Phase, also known as the growth phase, is the active period of hair growth in the hair cycle. During this phase, hair follicles are actively producing new hair cells, leading to the elongation of the hair shaft. This phase can last anywhere from 2 to 7 years, depending on genetic factors, and determines the maximum length of the hair.

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Adenosine Stimulates Growth of Dermal Papilla and Lengthens the Anagen Phase by Increasing the Cysteine Level via Fibroblast Growth Factors 2 and 7 in an Organ Culture of Mouse Vibrissae Hair Follicles

research Adenosine Stimulates Growth of Dermal Papilla and Lengthens the Anagen Phase by Increasing the Cysteine Level via Fibroblast Growth Factors 2 and 7 in an Organ Culture of Mouse Vibrissae Hair Follicles

28 citations, October 2011 in “International Journal of Molecular Medicine”

Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.

research Induction of the Hair Growth Phase in Postnatal Mice by Localized Transient Expression of Sonic Hedgehog

231 citations, October 1999 in “Journal of Clinical Investigation”

Activating the Sonic hedgehog gene in mice can start the hair growth phase.

research Exogen, Shedding Phase of the Hair Growth Cycle: Characterization of a Mouse Model

107 citations, September 2002 in “Journal of Investigative Dermatology”

Researchers found that hair shedding happens mostly when new hair is growing and involves a unique process.

Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells

research Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells

15 citations, May 2020 in “BMC complementary medicine and therapies”

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.

18-β-Glycyrrhetinic Acid Promotes Hair Growth by Stimulating the Proliferation of Dermal Papilla Cells and Outer Root Sheath Cells, and Extends the Anagen Phase by Inhibiting 5α-Reductase

research 18-β-Glycyrrhetinic Acid Promotes Hair Growth by Stimulating the Proliferation of Dermal Papilla Cells and Outer Root Sheath Cells, and Extends the Anagen Phase by Inhibiting 5α-Reductase

July 2024 in “Biological and Pharmaceutical Bulletin”

Licorice extract helps hair growth and may treat hair loss.

research Noggin Is Required for Induction of the Hair Follicle Growth Phase in Postnatal Skin

211 citations, October 2001 in “The FASEB Journal”

Noggin is necessary to start the hair growth phase in skin after birth.

research Aqueous Extract of Red Deer Antler Promotes Hair Growth by Regulating the Hair Cycle and Cell Proliferation in Hair Follicles

4 citations, January 2014 in “The Scientific World Journal”

Red deer antler extract helps hair grow by extending the growth phase and increasing cell growth in hair follicles.

research Exposure to Gamma-Rays at the Telogen Phase of the Hair Cycle Inhibits Hair Follicle Regeneration at the Anagen Phase in Mice

6 citations, November 2013 in “International Journal of Radiation Biology”

Gamma-rays exposure during the resting phase of hair growth can damage hair regeneration and color in mice.

research Potential of Colostrum-Derived Exosomes for Promoting Hair Regeneration Through the Transition from Telogen to Anagen Phase

5 citations, March 2022 in “Frontiers in Cell and Developmental Biology”

Colostrum-derived exosomes can promote hair growth and may be a promising treatment for hair loss.

research The Role of Mimicking Growth Factors to Control Anagen Phase: Evaluation In Vitro and In Vivo

February 2010 in “Journal of The American Academy of Dermatology”

Mimicking growth factors in a topical solution can prolong hair growth phase and reduce hair loss without side effects.

research Melanogenesis Is Coupled to Murine Anagen: New Concepts for the Role of Melanocytes and Regulation of Melanogenesis in Hair Growth

109 citations, July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

research De Novo Production of Dermal Papilla Cells During the Anagen Phase of the Hair Cycle

41 citations, June 2010 in “Journal of Investigative Dermatology”

New cells are added to the hair's dermal papilla during the active growth phase.

research Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle

120 citations, November 2014 in “Biological Reviews”

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

research Morroniside Regulates Hair Growth and Cycle Transition via Activation of the Wnt/β-Catenin Signaling Pathway

25 citations, September 2018 in “Scientific Reports”

Morroniside may help hair grow and stay in its growth phase by affecting certain cell signals.

research Pilose Antler Extract Promotes Hair Growth in Androgenic Alopecia Mice by Promoting the Initial Anagen Phase

April 2024 in “Biomedicine & pharmacotherapy”

Pilose antler extract helps hair grow in mice with a type of hair loss by speeding up the growth phase.

research De Novo Production of Dermal Papilla Cells During the Anagen Phase of the Hair Cycle

December 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

New cells join the hair's dermal papilla during the growth phase, possibly affecting hair thickness.

Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth

research Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth

210 citations, July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Scientific Opinion on the Substantiation of a Health Claim Related to Spermidine and Prolongation of the Growing Phase (Anagen) of the Hair Cycle Pursuant to Article 13(5) of Regulation (EC) No 1924/2006

research Scientific Opinion on the Substantiation of a Health Claim Related to Spermidine and Prolongation of the Growing Phase (Anagen) of the Hair Cycle Pursuant to Article 13(5) of Regulation (EC) No 1924/2006

1 citations, December 2011 in “EFSA Journal”

Spermidine may help extend the growth phase of hair.

A Spermidine-Based Nutritional Supplement Prolongs the Anagen Phase of Hair Follicles in Humans: A Randomized, Placebo-Controlled, Double-Blind Study

research A Spermidine-Based Nutritional Supplement Prolongs the Anagen Phase of Hair Follicles in Humans: A Randomized, Placebo-Controlled, Double-Blind Study

8 citations, October 2017 in “Dermatology practical & conceptual”

A spermidine-based supplement may help hair grow longer by keeping it in the growth phase.

research Promotion Effect of Apo-9'-Fucoxanthinone from Sargassum Muticum on Hair Growth via the Activation of Wnt/β-Catenin and VEGF-R2

19 citations, January 2016 in “Biological & Pharmaceutical Bulletin”

Sargassum muticum extract and its component apo-9'-fucoxanthinone may help hair growth and treat hair loss.

research Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth

3 citations, August 2020 in “International Journal of Molecular Sciences”

Blocking Rab27a slows hair growth, while blocking Rab27b encourages it.

research The Effect of Topical Minoxidil on Hair Follicular Cycles of Rats

53 citations, May 1990 in “Journal of Dermatology”

Minoxidil speeds up hair growth in rats without prolonging growth phase.

In Vivo and In Vitro Evaluation of Hair Growth Potential of Cacumen Platycladi, and GC-MS Analysis of the Active Constituents of Volatile Oil

research In Vivo and In Vitro Evaluation of Hair Growth Potential of Cacumen Platycladi, and GC-MS Analysis of the Active Constituents of Volatile Oil

13 citations, March 2019 in “Journal of ethnopharmacology”

Cacumen Platycladi oil promotes hair growth better than minoxidil.

research Hair Growth Promoting Effect of 4HGF Encapsulated with PGA Nanoparticles by β-Catenin Activation and Related Cell Cycle Molecules

7 citations, July 2019 in “International Journal of Molecular Sciences”

PGA-4HGF may help treat hair loss by activating hair growth pathways and extending the hair growth phase.

Hair Growth Effect and the Mechanisms of Rosa Rugosa Extract in DHT-Induced Alopecia Mice Model

research The Effect of Cilostazol, a Phosphodiesterase 3 (PDE3) Inhibitor, on Human Hair Growth with Dual Promoting Mechanisms

21 citations, April 2018 in “Journal of Dermatological Science”

Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.

research Chrysanthemum Zawadskii Extract Induces Hair Growth by Stimulating the Proliferation and Differentiation of Hair Matrix

12 citations, May 2014 in “International Journal of Molecular Medicine”

Chrysanthemum zawadskii extract helps hair grow by stimulating hair cells.

research Cucurbitacin Promotes Hair Growth in Mice by Inhibiting the Expression of Fibroblast Growth Factor 18

1 citations, October 2022 in “Annals of Translational Medicine”

Cucurbitacin helps mice grow hair by blocking a protein that stops hair growth.

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Products matching "growth phase of the hair"

Research

research Adenosine Stimulates Growth of Dermal Papilla and Lengthens the Anagen Phase by Increasing the Cysteine Level via Fibroblast Growth Factors 2 and 7 in an Organ Culture of Mouse Vibrissae Hair Follicles

research Induction of the Hair Growth Phase in Postnatal Mice by Localized Transient Expression of Sonic Hedgehog

research Exogen, Shedding Phase of the Hair Growth Cycle: Characterization of a Mouse Model

research Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells

research 18-β-Glycyrrhetinic Acid Promotes Hair Growth by Stimulating the Proliferation of Dermal Papilla Cells and Outer Root Sheath Cells, and Extends the Anagen Phase by Inhibiting 5α-Reductase

research Noggin Is Required for Induction of the Hair Follicle Growth Phase in Postnatal Skin

research Aqueous Extract of Red Deer Antler Promotes Hair Growth by Regulating the Hair Cycle and Cell Proliferation in Hair Follicles

research Exposure to Gamma-Rays at the Telogen Phase of the Hair Cycle Inhibits Hair Follicle Regeneration at the Anagen Phase in Mice

research Potential of Colostrum-Derived Exosomes for Promoting Hair Regeneration Through the Transition from Telogen to Anagen Phase

research The Role of Mimicking Growth Factors to Control Anagen Phase: Evaluation In Vitro and In Vivo

research Melanogenesis Is Coupled to Murine Anagen: New Concepts for the Role of Melanocytes and Regulation of Melanogenesis in Hair Growth

research De Novo Production of Dermal Papilla Cells During the Anagen Phase of the Hair Cycle

research Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle

research Morroniside Regulates Hair Growth and Cycle Transition via Activation of the Wnt/β-Catenin Signaling Pathway

research Pilose Antler Extract Promotes Hair Growth in Androgenic Alopecia Mice by Promoting the Initial Anagen Phase

research De Novo Production of Dermal Papilla Cells During the Anagen Phase of the Hair Cycle

research Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth

research Scientific Opinion on the Substantiation of a Health Claim Related to Spermidine and Prolongation of the Growing Phase (Anagen) of the Hair Cycle Pursuant to Article 13(5) of Regulation (EC) No 1924/2006

research A Spermidine-Based Nutritional Supplement Prolongs the Anagen Phase of Hair Follicles in Humans: A Randomized, Placebo-Controlled, Double-Blind Study

research Promotion Effect of Apo-9'-Fucoxanthinone from Sargassum Muticum on Hair Growth via the Activation of Wnt/β-Catenin and VEGF-R2

research Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth

research The Effect of Topical Minoxidil on Hair Follicular Cycles of Rats

research In Vivo and In Vitro Evaluation of Hair Growth Potential of Cacumen Platycladi, and GC-MS Analysis of the Active Constituents of Volatile Oil

research Hair Growth Promoting Effect of 4HGF Encapsulated with PGA Nanoparticles by β-Catenin Activation and Related Cell Cycle Molecules

research Hair Growth Effect and the Mechanisms of Rosa Rugosa Extract in DHT-Induced Alopecia Mice Model

research In Vivo Study of the Effect of 5% and 10% Nebivolol Cream on Hair Growth in Mice Models

research Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells

research The Effect of Cilostazol, a Phosphodiesterase 3 (PDE3) Inhibitor, on Human Hair Growth with Dual Promoting Mechanisms

research Chrysanthemum Zawadskii Extract Induces Hair Growth by Stimulating the Proliferation and Differentiation of Hair Matrix

research Cucurbitacin Promotes Hair Growth in Mice by Inhibiting the Expression of Fibroblast Growth Factor 18