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This commentary highlights that transgender patients are often dissatisfied with standard hormone replacement therapy for hair-related goals, emphasizing the need for dermatologists to provide informed guidance and tailor treatments.

This case report describes a 65-year-old woman with childhood-onset growth hormone deficiency who developed panhypopituitarism, including late-onset secondary hypoadrenocorticism, affecting her respiratory and renal function.

This review discusses the effects of estrogen on skin and reports no new clinical results; it highlights estrogen's potential benefits on skin thickness, collagen quality, and hair follicle life cycle.

In this study, female patients undergoing hormone replacement therapy showed improvements in frontal hairline appearance and increased hair plucking strength, suggesting positive effects of estradiol on hair growth while excluding age-related factors.

This study found that GnRH-A treatment significantly reduced hirsuties scores in women with mild idiopathic hirsuties but did not affect hair growth rate or diameter.

This study found that MENT is 10 times more potent than testosterone in suppressing gonadotropins and contributing to anabolism in monkeys, with a potentially wider therapeutic index for human androgen replacement and male contraception.

This study by Dr. Manka and colleagues reported that thyroid hormones play a significant role in regulating hepatic stellate cells, influencing liver fibrosis progression via TGFβ signaling. They found that TRα signaling might enhance scar-free tissue regeneration, offering potential pathways for targeted liver fibrosis treatments.

This review outlines the benefits of menopausal hormone therapy for improving skin properties in peri- and postmenopausal women, emphasizing that interdisciplinary management enhances quality of life but noting the aesthetic improvements are secondary outcomes.

This article discusses the potential benefits of platelet-rich plasma injections in ovarian tissue to improve reproductive outcomes in IVF for older individuals and proposes a mechanism to enhance embryo ploidy rescue, but reports no new clinical results.

In this case report, a transgender woman with refractory epilepsy began estrogen therapy for gender-affirming purposes, experiencing stable epilepsy and reduced gender dysphoria through ongoing multidisciplinary care, highlighting the importance of careful management for similar patients.

This article reviews surgical hair replacement techniques for bald patients dissatisfied with hairpieces and reports that various options provide good results with minimal side effects, emphasizing the importance of frontal area design for a natural appearance.

This study found that treatment with a GnRH agonist and estrogen and progestin replacement significantly improved hirsutism scores and hair growth rates in women with polycystic ovarian disease.

This article reviews the clinical signs, diagnostic approaches, and treatment options for hyperandrogenism in women, focusing on hirsutism and specifies that cyproterone acetate is effective for severe cases, but reports no new clinical results.

This case report highlights that Sheehan syndrome, though rare in developed countries, can occur and underscores the importance of detailed history taking to uncover the cause of atypical presentations.

This article reviews the role of hormones in human penis development and associated conditions due to hormonal imbalances, but reports no new findings, suggesting hormone replacement can manage some conditions.

This case report describes an unusual variant of Turner Syndrome in a 20-year-old female that required comprehensive medical and psychological care, including hormonal therapy that resolved symptoms like alopecia.

In this study, researchers observed that administering the minimum dose of levothyroxine to a hypothyroid Dalmatian effectively restored normal skin condition and hormonal levels, suggesting levothyroxine's potential effectiveness in managing skin changes caused by hypothyroidism in dogs.

This review discusses the diagnosis and treatment of 21-hydroxylase deficiency in congenital adrenal hyperplasia and emphasizes the need for earlier detection and proper management; it reports no clinical results.

This review indicates that estrogen loss during menopause significantly impacts skin health, while estrogen treatment may increase skin collagen, thickness, and elasticity, though effects on other skin characteristics are inconsistent.

This review discusses the effects of estrogens on skin aging and highlights the potential benefits of estrogen replacement therapy and selective estrogen receptor modulators for improving skin health in postmenopausal women, but reports no new clinical findings.

This review discusses the pharmacological properties of progestins used in contraception and hormone replacement therapy, focusing on drospirenone's unique effects, but reports no new experimental findings.

This review discusses the impact of HRT on menopausal skin and hair symptoms and argues that potential benefits should be part of informed decision-making for managing menopause.

Menopause affects skin and hair, and more research is needed for effective treatments.

This review discusses factors affecting hair aging, such as inflammation and UV exposure, and examines potential anti-aging benefits of antioxidants and nutraceuticals for hair, but reports no new clinical results.

In this study, Brazilian postmenopausal women reported that menopause significantly deteriorates the quality of their skin, nails, and hair, negatively affecting self-esteem and quality of life, with a need for better understanding of hormone replacement therapy's dermatological effects.

This article reviews anti-aging strategies in dermatology, emphasizing the role of skin as a model for studying aging and promoting preventive and therapeutic interventions, but it does not present new findings.

This review examines the effects of menopause on skin aging and suggests hormone replacement therapy may improve some symptoms, without providing new clinical findings.

This study reported that cortisone, testosterone, and thyroxine replacement therapy increased energy and hair growth, while decreasing cold sensitivity, in the absence of tumor recurrence.

Estetrol may help prevent hair loss and support hair growth in women.

This case report from a pediatric setting highlighted how an 11-year-old with Hashimoto thyroiditis experienced atypical manifestations such as short stature, pubertal issues, and hair loss after starting levothyroxine therapy, underscoring the need for early diagnosis and multidisciplinary care to improve health outcomes.