research Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia
Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
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research Mucocutaneous Manifestations of Endocrine Disorders
Skin symptoms can indicate endocrine disorders and have various treatments.
research TR3 Is Preferentially Expressed by Bulge Epithelial Stem Cells in Human Hair Follicles
TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
research Clinical Use of 5α-Reductase Inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
research Updates on Hirsutism: A Narrative Review
The review suggests a comprehensive approach to treat hirsutism, focusing on hair removal, medication, and managing emotional effects.
research Past and Future Strategies for GPCR Deorphanization
Finding functions for unknown GPCRs is hard but key for making new drugs.
research Hair Restoration: An Overview of Anatomy, Causes, and Treatments
The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.
research Androgenetic Alopecia
AGA is a common hair loss affecting both genders, treated with various therapies to promote regrowth and slow thinning.
research A Review of Coumarin Derivatives in Pharmacotherapy of Breast Cancer
Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
research Dermatologic Manifestations of Endocrine Disorders
Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.
research Male Androgenetic Alopecia
DHT, a testosterone byproduct, causes male pattern baldness.
research Hirsutism: Diagnosis and Management
The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.
research Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs
Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.
research Treatment of Alopecia X with Medroxyprogesterone Acetate
Medroxyprogesterone injections caused hair regrowth in some dogs with alopecia X.
research Dasatinib-Induced Leukotrichia in a Patient With Chronic Myelogenous Leukemia
A woman's hair turned white after taking a cancer drug called dasatinib.
research The Anti-Androgen Combination, Flutamide Plus Finasteride, Paradoxically Suppressed LH and Androgen Concentrations in Pregnant Spotted Hyenas, but Not in Males
Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.
research Nonscarring Hair Loss Disorders
Most types of hair loss can regrow naturally, but there are no effective cures for male pattern or age-related hair loss, and only limited options for females.
research Down-Ranking the Threat of HSV-1: RANKL Upregulates MHC Class I Restricted Anti-Viral Immunity in Herpes Simplex Virus Infection
RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.
research Susan Lee Lindquist (1949–2016)—Pioneer in the Study of Cellular Protein Folding and Disease
Susan Lee Lindquist was a pioneering biologist who made significant contributions to understanding protein folding and its role in disease.
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research Antiandrogens and Androgen Inhibitors in Dermatologic Treatments
Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
research Zinc Therapy in Dermatology: A Review
Zinc is effective for treating various skin conditions, including warts and acne.
research Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis
The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.
research Testosterone Supplementation for Aging-Associated Sarcopenia
Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.
research Steroids And Steroid-Like Compounds
Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.
research Prolactin: An Emerging Force Along the Cutaneous–Endocrine Axis
Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
research Novel Agents for the Treatment of Alopecia
New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.
research Topical Cyperus Rotundus Oil
Cyperus rotundus oil effectively reduces unwanted hair without side effects.
research The Safety of Testosterone Therapy in Women
Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.
research Controversy: Is There a Role for Adjuvants in the Management of Male Pattern Hair Loss?
Adjuvants, diet changes, and laser therapy may improve male pattern hair loss.