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The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.

Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Researchers created hair-inducing human cell clusters using a 3D culture method.

People with late-stage HIV-1 often experience a specific type of hair loss linked to multiple factors, including nutritional issues and immune responses.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.

Minoxidil may cause heart issues in animals and humans.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Human placenta hydrogel helps restore cells needed for hair growth.

The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.

Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.

Somatostatin may help protect hair follicles from immune attacks.

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

Soy isoflavones can protect lung tissue from radiation damage.

The document concludes that veterinary dermatologists need more experience and a better approach to treating skin diseases in nonhuman primates.

α-type filaments in guinea pig hair follicles have unique structural features.