118 citations
,
November 2024 in “World Journal of Biology Pharmacy and Health Sciences” This study highlights that the ACIP strongly recommends COVID-19 vaccination and booster doses for pregnant women, those breastfeeding, or trying to conceive, due to the safety of non-live vaccines in these groups and the protection they also offer to infants.
118 citations
,
August 2010 in “Developmental Cell” This study found that the protein MIM is crucial for maintaining cilia and Sonic hedgehog signaling in mesenchymal cells by counteracting Src-mediated phosphorylation of Cortactin, impacting hair follicle formation.
115 citations
,
January 2014 in “Journal of Cutaneous and Aesthetic Surgery” In this study, PRP injections increased hair count and reduced hair loss in patients with androgenic alopecia not responding to minoxidil and finasteride, with high patient satisfaction reported.
115 citations
,
November 1999 in “Journal of The American Academy of Dermatology” In this study, men using 2% and 5% minoxidil solutions experienced a significant increase in hair weight for 96 weeks compared to placebo, with effects diminishing after treatment cessation.
114 citations
,
March 2021 in “Scientific Reports” This study found that, among COVID-19 patients in South Korea, hypertension, diabetes, and other comorbidities significantly increased mortality risk, with the age-adjusted Charlson comorbidity index being a strong predictor of death.
113 citations
,
March 2018 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society” This review examines the adaptive value and mechanisms of seasonal coat colour moulting in birds and mammals, highlighting the challenge of camouflage mismatch and the necessity for evolutionary adaptation under climate change.
109 citations
,
December 2003 in “American Journal of Pathology” This study observed that the ontogenetic transition from scarless repair in early fetal rat wounds to scar-forming repair in late gestation is associated with differential TGF-β ligand and receptor expression patterns.
106 citations
,
March 2014 in “BioEssays” This review examines current knowledge on human epithelial hair follicle stem cells, their markers, and outlines challenges in translating findings from murine studies to human research, but does not report new experimental results.
105 citations
,
August 2010 in “Pharmacology & therapeutics” This article explores the potential of formyl-peptide receptor 2 agonists as innovative anti-inflammatory drugs, highlighting their ability to mimic the body's natural inflammation response, but it presents no new clinical findings.
105 citations
,
February 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.
103 citations
,
June 2007 in “Endocrinology and Metabolism Clinics of North America” This article discusses treatment options for androgenetic alopecia, noting that medical interventions like finasteride and minoxidil can halt and partially reverse hair loss in mild to moderate cases, especially when combined with surgery.
99 citations
,
July 2012 in “PLoS Genetics” This study identified a 69 bp deletion in the KRT75 gene as the cause of the frizzle feather trait in chickens, affecting feather curling.
98 citations
,
August 2004 in “BJU international” This review critically examines the current medical management strategies for BPH/LUTS and reports no new experimental results.
96 citations
,
October 2000 in “The FASEB Journal” In this study, researchers found that p75 neurotrophin receptor signaling affects apoptosis during hair follicle regression in mice, and altering its activity might help manage disorders involving early catagen entry.
95 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.
91 citations
,
August 2014 in “Development” This review discusses how circadian clocks may influence diverse physiological functions beyond their established role in daily timekeeping, but it reports no new experimental findings.
91 citations
,
January 2009 in “International Journal of Trichology” This review discusses the advantages and limitations of various hair loss evaluation methods but reports no new results; it emphasizes the importance of cautious interpretation for these diagnostic tools.
90 citations
,
October 1998 in “Animal Reproduction Science” This study found that in captive mouflon rams, reproductive and physical maturation, marked by changes in hormone levels and physical attributes, progresses gradually across their life span, with sexual maturity tied closely to physical maturity.
89 citations
,
November 2014 in “International Journal of Nanomedicine” This study suggests that spironolactone-loaded nanostructured lipid carriers could enhance follicular delivery and offer a more localized treatment for androgenic alopecia, potentially reducing systemic side effects.
88 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article reviews recent advancements in understanding and treating androgenetic alopecia, focusing on new genetic insights, stem cell roles, and diagnostic tools, without reporting new clinical results.
87 citations
,
March 2020 in “Australian Dental Journal” This review discusses different preparation and application methods of platelet-rich plasma in dental regenerative medicine and reports no new results, highlighting its potential and associated controversies.
86 citations
,
August 2014 in “Journal of The American Academy of Dermatology” This article discusses the history taking and clinical examination process for diagnosing alopecia and outlines a diagnostic approach, noting that it reports no new clinical results.
85 citations
,
March 2002 in “Body & Society” This article reviews the discourse around male cosmetic surgery patients and argues against the perception that cosmetic surgery will become as common among men as it is among women.
84 citations
,
January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” This article reviews recent advancements in understanding skin stem cells and their roles in maintaining epidermal homeostasis and repairing wounds, without presenting new experimental findings.
83 citations
,
June 2018 in “Frontiers in immunology” This review discusses the roles of αβ and γδ T cells in skin health and disease and reports no new clinical results; the authors highlight potential therapeutic developments.
82 citations
,
May 2016 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” This article outlines the clinical features, evaluation, and treatment strategies for androgen excess in polycystic ovary syndrome, highlighting important diagnostic and management approaches but reporting no new research results.
80 citations
,
October 1985 in “American Journal of Public Health” This study found significant weight loss and reductions in blood pressure and serum triglycerides among obese patients following a multidisciplinary program with a very low calorie ketogenic diet.
77 citations
,
February 2017 in “Stem Cell Reports” This study found that activation of Wnt/β-catenin signaling in mouse testes promotes spermatogonial differentiation and reduces the stem cell pool, with SHISA6 inhibiting this process and maintaining stem cell characteristics.
77 citations
,
April 1999 in “Dermatologic Clinics” This article reviews how new observations have revolutionized surgical hair restoration and highlights the logical applications and prior illogical judgments that delayed this advancement, without reporting new results.
76 citations
,
January 2017 in “World Journal of Stem Cells” This review discusses the potential applications of adipose-derived stromal cells for treating conditions like colitis, liver failure, and more, without presenting new clinical results.