research Screening of Euphorbiaceae Plant Extracts for Anti-5α-Reductase Activity
Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.
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research Self-Assembled Chitosan Nanoparticles for Percutaneous Delivery of Caffeine: Preparation, Characterization, and In Vitro Release Studies
Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.
research Cutaneous Transcriptome Analysis in NIH Hairless Mice
Key genes linked to hair growth and cancer were identified in hairless mice.
research A Comparative In Vivo and In Vitro Evaluation of Hair Growth Potential of Extracts and an Isolate from Petroleum Ether Extract of Cuscuta Reflexa Roxb
Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.
![Synthesis, Biological Evaluation, and Molecular Docking of 4-Amino-2H-benzo[h]chromen-2-one Analogs Containing the Piperazine Moiety](/images/research/2ecf4eed-7dbe-4f1a-83db-739625546cdd/small/31808.jpg)
research Synthesis, Biological Evaluation, and Molecular Docking of 4-Amino-2H-benzo[h]chromen-2-one Analogs Containing the Piperazine Moiety
Analog 23 is a promising compound for prostate cancer treatment.
research 11α-Hydroxyprogesterone, a Potent 11β-Hydroxysteroid Dehydrogenase Inhibitor, Is Metabolized by Steroid-5α-Reductase and Cytochrome P450 17α-Hydroxylase/17,20-Lyase to Produce C11α-Derivatives of 21-Deoxycortisol and 11-Hydroxyandrostenedione In Vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
research Synthesized Ceramide Induces Growth of Dermal Papilla Cells with Potential Contribution to Hair Growth
Synthetic ceramides may help hair growth by boosting cell growth in hair follicles.
research Proprietary Herbal Extract Downregulates the Gene Expression of IL-1α in HaCaT Cells: Possible Implications Against Nonscarring Alopecia
A herbal extract may help treat certain types of hair loss by reducing a specific gene's activity.
research A Clinician's Approach to the Investigation of Otitis Externa
The document concludes that a thorough examination and various tests are crucial for diagnosing and treating ear inflammation in pets.
research Non-Rhizobial Nodule Endophytes Improve Nodulation, Change Root Exudation Pattern and Promote the Growth of Lentil for Prospective Application in Fallow Soil
Certain bacteria can boost lentil growth and improve soil used for farming.
research Efficacy and Safety of a Topical Botanical in Female Androgenetic Alopecia: A Randomized, Single-Blinded, Vehicle-Controlled Study
Topical botanical lotion increases hair density and improves quality of life in women with hair loss.
research Decoction and Fermentation of Selected Medicinal Herbs Promote Hair Regrowth by Inducing Hair Follicle Growth in Conjunction with Wnt Signaling
Boiling and fermenting certain herbs can help hair grow by activating hair growth genes and pathways.
research Integration Analysis of Transcriptome and Proteome Reveals the Mechanisms of Goat Wool Bending
The research identified key proteins and genes that may influence wool bending in goats.
research Inhibition of Class I HDACs Preserves Hair Follicle Inductivity in Postnatal Dermal Cells
Inhibiting class I HDACs helps maintain hair growth ability in skin cells.
research Essential Role of STAT3 Signaling in Hair Follicle Homeostasis
STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
research Optogenetically Controlled TrkA Activity Improves the Regenerative Capacity of Hair-Follicle-Derived Stem Cells to Differentiate into Neurons and Glia
Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.
research Septin4 Promotes Cell Death in Human Colon Cancer Cells by Interacting with BAX
Septin4 helps kill colon cancer cells by working with the protein BAX.
research Wound Healing Mechanism in Mongolian Gerbil Skin
Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.
research Bioactives in Chinese Proprietary Medicine Modulate 5α-Reductase Activity and Gene Expression Associated with Androgenetic Alopecia
Chinese medicine may help treat hair loss by affecting genes and enzyme activity.
research Dermal-Epidermal Cross-Talk: Differential Interactions With Microvascular Endothelial Cells
Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.
research Luxury Hair Fibers for the Fashion Industry
The industry should promote pure luxury hair fibers, improve technology, and diversify products to support growers and ensure sustainable use.
research Deciphering the Mesodermal Potency of Porcine Skin-Derived Progenitors by Microarray Analysis
Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
research Discovery of Differentially Expressed Genes in Cashmere Goat Hair Follicles by RNA Sequencing
Researchers found 617 genes that behave differently in cashmere goat hair follicles, which could help understand hair growth.
research Differential Impact of Environmental Factors on Systemic and Localized Autoimmunity
Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
research Selective Expansion of Tregs Using the IL-2 Cytokine Antibody Complex Does Not Reverse Established Alopecia Areata in C3H/HeJ Mice
Increasing Treg cells in the skin does not cure hair loss from alopecia areata in mice.
research Glioblastoma Cells Express Crucial Enzymes Involved in Androgen Synthesis: 3β-Hydroxysteroid Dehydrogenase, 17-20α-Hydroxylase, 17β-Hydroxysteroid Dehydrogenase, and 5α-Reductase
Glioblastoma cells can make androgens, which might help the tumor grow.
research Integrin α3β1 in Hair Bulge Stem Cells Modulates CCN2 Expression and Promotes Skin Tumorigenesis
Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.
research Sub-Chronic Effects of a Phthirusa Pyrifolia Aqueous Extract on Reproductive Function and Comparative Hormone Levels in Male Rats
Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.
research Techniques for the Discovery and Evaluation of Drugs Against Alopecia
We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.