research A Powerful Method for Pleiotropic Analysis Under Composite Null Hypothesis Identifies Novel Shared Loci Between Type 2 Diabetes and Prostate Cancer
New method finds genetic links between Type 2 Diabetes and Prostate Cancer not seen before.
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390-420 / 1000+ results research A Review of Scalp Camouflaging Agents and Prostheses for Individuals with Hair Loss
Using wigs, hairpieces, and sprays can help people with hair loss feel better about themselves.
research Two Cases of Alopecia Areata Treated with Ruxolitinib: A Discussion of Ideal Dosing and Laboratory Monitoring
Ruxolitinib effectively and safely regrows hair in alopecia patients.
research Encapsulation of Curcumin in Polystyrene-Based Nanoparticles: Drug Loading Capacity and Cytotoxicity
Curcumin can be effectively loaded into polystyrene nanoparticles, which are safe for human cells and more biocompatible with curcumin inside.
research Weekly Azathioprine Pulse Versus Betamethasone Oral Mini-Pulse in the Treatment of Moderate-to-Severe Alopecia Areata
Weekly azathioprine pulse is a better alternative to corticosteroids for treating alopecia areata due to fewer side effects.
research Atypical Hippocampal Glutamate Receptor Coupled to Phospholipase D Controlling Stretch-Sensitivity in Primary Mechanosensory Nerve Endings Is Homomeric Purely Metabotropic GluK2
A special receptor in sensory nerve endings helps control how they respond to stretching.
research Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg-like Cells, and Common EGFR Somatic Mutations
Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.
research Abstracts from the 4th Annual Student Medical Summit
The document concludes that more research is needed to reduce frequent hospital visits, addiction medicine education improves with specific training, early breast cancer surgery findings are emerging, nipple smears are not very accurate, surgery for older melanoma patients doesn't extend life, a genetic condition in infants can often be treated with one drug, doctors are inconsistent with blood clot medication, a certain gene may protect against cell damage, muscle gene overexpression affects many other genes, and some mitochondrial genes are less active in mice with tumors.
research Cardamonin-Loaded Liposomal Formulation for Improving Percutaneous Penetration and Follicular Delivery for Androgenetic Alopecia
A new liposomal formulation improves drug delivery and hair growth for treating hair loss without causing skin irritation.
research Interactions Between Damaged Hair Keratin and Juglone as a Possible Restoring Agent: A Vibrational and Scanning Electron Microscopy Study
Juglone from walnut extracts may help repair damaged hair.
research Long-Term Prophylaxis With Androgens in the Management of Hereditary Angioedema in Emerging Countries
Long-term use of androgens can help manage Hereditary Angioedema (HAE) but may cause serious side effects, so alternative treatments with fewer side effects are being considered.
research Genome-Wide Detection of RNA Editing Events During the Hair Follicles Cycle of Tianzhu White Yak
RNA editing significantly affects hair growth and follicle cycling in the Tianzhu white yak.
research The Role of Candidate Pharmacogenetic Variants in Determining Valproic Acid Efficacy, Toxicity, and Concentrations in Patients with Epilepsy
Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.
research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
research Prevalence of Polycystic Ovary Syndrome and Its Associated Complications in Iranian Women: A Meta-Analysis
Polycystic Ovary Syndrome (PCOS) is not very common among Iranian women, but it's important to prevent it because of the risk of heart disease and infertility.
research How Coronavirus Disease 2019 Changed Dermatology Practice in One Year Around the World
COVID-19 changed dermatology by increasing telemedicine and highlighting healthcare disparities.
research The Human Hair Follicle as Sentinel for Drug Evaluation: Demonstration of Tetracycline Adhesion to Hair Follicle as Proposed Mechanism in Dysfunctional Hair Loss
Tetracycline can stick to hair follicles and potentially cause hair loss.
research Why Some Women Look Young for Their Age
Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.
research Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases
Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.
research DKK1 Mediated Inhibition of Wnt Signaling in Postnatal Mice Leads to Loss of TEC Progenitors and Thymic Degeneration
Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
research Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage
Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.
research Meis1 Regulates Epidermal Stem Cells and Is Required for Skin Tumorigenesis
Meis1 is crucial for skin health and tumor development.
research HGF/SF Increases Number of Skin Melanocytes but Does Not Alter Quality or Quantity of Follicular Melanogenesis
HGF/SF increases skin melanocytes but doesn't change melanin type or amount.
research Preventive and Therapeutic Efficacy of Finasteride and Dutasteride in TRAMP Mice
Dutasteride works better than finasteride for preventing and treating prostate cancer.
research FC056 The Ideal Catagen of the Hair
Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.
research Methods for Quantifying Intrafollicular Drug Delivery: A Critical Appraisal
The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
research Topical Gene Electrotransfer to the Epidermis of Hairless Guinea Pig by Non-Invasive Multielectrode Array
The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.
research The Okuda Papers: An Extraordinary But Unfortunately Unrecognized Piece of Work That Could Have Changed the History of Hair Transplantation
Dr. Shoji Okuda's pioneering work on hair transplantation was overlooked and could have significantly advanced the field if recognized sooner.
research Deep Plane Fixation in Integumental Surgery
Deep Plane Fixation in scalp surgeries allows for more tissue removal with less tension, leading to better healing and less scarring.
research Granulomatous Alopecia Areata
A woman's rare hair loss condition improved on its own, suggesting this type might recover like common cases.