October 2022 in “Hair Transplantation” This paper discusses factors for successful graft production in hair restoration but presents no new findings, emphasizing the importance of technical knowledge and skilled surgical teams for optimal results.
November 1998 in “Hair transplant forum international” This article discusses recent advancements in hair restoration techniques, focusing on optimizing efficiency for megasession procedures, and reports no new experimental results.
10 citations
,
November 1997 in “British Journal of Dermatology” This study found that the non-steroidal antiandrogen RU58841 increased hair growth rates and promoted hair cycle initiation in balding human scalp grafts on testosterone-conditioned nude mice, indicating a positive effect on hair growth.
9 citations
,
November 1997 in “British Journal of Dermatology”
2 citations
,
September 2023 in “Curēus” This study reported that topical spironolactone improved lid margin vascularity, corneal fluorescein staining, and disease severity scores in patients with ocular graft-versus-host disease, suggesting a potential therapeutic role by enhancing corneal lipid production with minimal adverse effects.
December 2012 in “Journal of dermatological science” This study reveals that hair follicles in mice and humans recruit epidermal Langerhans cells during skin inflammation via specific chemokine signaling pathways.
November 2025 in “SHILAP Revista de lepidopterología” This review systematically evaluates 13 animal and 2 mathematical models for alopecia areata, assessing their effectiveness in understanding the condition's pathogenesis and aiding in the development of new therapeutic strategies.
1 citations
,
November 2009 in “Cambridge University Press eBooks” This article reports that follicular unit extraction is a minimally invasive hair restoration technique that avoids linear scarring and reduces donor-site pain compared to traditional strip harvesting methods.
152 citations
,
December 2007 in “Gender Medicine” This review discusses recent advances in understanding gender differences in skin and their implications for dermatologic diseases, but it reports no new experimental results; ongoing research is necessary for translating these insights into clinical practice.
150 citations
,
August 1992 in “Genes & Development” This study reported that transgenic mice with targeted TNF alpha expression in keratinocytes showed impaired weight gain, retarded hair growth, and skin changes, leading to cachexia and necrosis.
2 citations
,
July 1994 in “Journal of Dermatological Science” This study found that a laboratory model using nude mice can produce human hair follicles with amino acid compositions resembling both normal and trichothiodystrophy-affected human scalp hair over extended periods.
7 citations
,
September 2014 in “Journal of Obstetrics and Gynaecology Research” This study found that the ovarian stromal area to total ovarian area ratio alone is not a strong predictor of biochemical hyperandrogenism in Thai women with PCOS, but combining it with clinical hyperandrogenism improves prediction.
9 citations
,
August 2013 in “Journal of Tissue Engineering and Regenerative Medicine” In this study, neonatal murine skin-derived cells transplanted using a mini-chamber method successfully produced robust and normal hair, contrasting with human scalp follicles which did not achieve follicle reconstruction.
This article reviews differences in hair characteristics between Asians and Caucasians, highlighting Asian hair's lower density and thicker dermis, and reports no new research findings.
44 citations
,
January 2013 in “BMC Dermatology” This study found that TGFβ signaling is essential for keeping sebocytes undifferentiated by reducing lipid-related gene expression, using a novel human sebocyte culture model.
48 citations
,
January 2018 in “Stem Cells International” This review discusses autologous tissue engineering strategies and skin-derived stem cell transplantation products, noting clinical challenges and highlighting ongoing trial activities, without reporting new clinical outcomes.
February 1997 in “Dermatologic Surgery” This review discusses mathematical correlations in hair restoration surgery but reports no new research findings.
1 citations
,
October 1996 in “Dermatologic clinics” This study found that higher levels of adiponectin were associated with reduced inflammation and osteolysis, suggesting potential therapeutic benefits for patients with aseptic loosening of joint replacements.
September 2024 in “Journal of the American Academy of Dermatology” In this pilot study, minoxidil-treated scalp skin grafts from hair loss patients on mice showed increased expression of key anti-aging biomarkers and hair regrowth, suggesting minoxidil as a potential anti-aging agent by boosting VEGF-A production in hair follicles.
August 2022 in “Tissue Engineering Part A” This study observed that using ex vivo gene therapy to modify skin cells in a pre-graft model improved dermal-epidermal junction adhesion strength and maintained collagen production over time, suggesting a potential treatment approach for recessive dystrophic epidermolysis bullosa skin wounds.
7 citations
,
July 2016 in “Journal of Biomedical Materials Research Part A” This study found that a novel hydrogel scaffold, cGEL, significantly increased melanin production and melanotic gene expression in human melanocytes compared to other graft materials, suggesting its potential as a superior carrier for skin grafting.
33 citations
,
May 2006 in “Journal of Investigative Dermatology” This study found that high levels of parathyroid hormone-related protein expression can result in the production of shorter hair shafts, likely through effects on angiogenesis.
5 citations
,
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports on an ongoing Phase I/IIa clinical trial of ex vivo gene therapy for treating severe Recessive Dystrophic Epidermolysis Bullosa, involving six adult participants with COL7A1 mutations resulting in deficient type VII collagen production.
This review highlights the potential of 3D bioprinting in developing functional, patient-specific artificial skin, addressing limitations of traditional skin grafts and advancing regenerative medicine applications.
21 citations
,
December 1994 in “British Journal of Dermatology” In this study, cultured skin equivalents with ovine hair follicle dermal papillae grafted onto nude mice developed follicle-like structures, suggesting a potential model for studying hair follicle development.
135 citations
,
December 2015 in “Expert Opinion on Biological Therapy” This review synthesizes recent research on exosomes, highlighting their role as key modulators in regenerative outcomes and suggesting they may offer advantages over stem cell-based therapies in process and regulation.
1 citations
,
July 2025 in “Stem Cell Research & Therapy” In this study, researchers evaluated hair follicle transplantation techniques and reported that challenges such as limited follicle supply and low follicle survival rates often limit patient satisfaction, but advances in regenerative medicine may offer promising new solutions.
January 2012 in “Elsevier eBooks” This chapter reviews therapies for skin and corneal regeneration and hair loss, discussing various treatments but presenting no new research findings.
December 2025 in “FEBS Open Bio” In this study, fibroblasts from long-term skin biopsy cultures retained their ability to reprogram into induced pluripotent stem cells after 16 months, despite undergoing transcriptional changes and decreased proliferation rates over successive generations.
1 citations
,
August 2000 in “Expert Opinion on Therapeutic Patents” This article reviews the therapeutic use of carnitine derivatives for re-establishing mitochondrial functionality in aging and reports no new clinical results.