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The supplement highlighted advancements and challenges in plastic and reconstructive surgery, including the impact of smoking, chemotherapy, and new treatments like Tafluprost for hair loss.

Lichen planus is a chronic autoimmune disease that is hard to treat and more common in women.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Researchers created human hair follicles using a new method that could help treat hair loss.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Hair follicle regeneration needs special conditions and young cells.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Tight hairstyles and chemical relaxers can cause hair loss known as traction alopecia.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Tattooing helps treat skin conditions, reconstruct nipple-areola, mark radiation fields, and locate lesions.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Multiple treatments work best for hair loss.

Burn reconstruction improves with new techniques, materials, and tissue engineering.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Microsurgical reconstruction effectively covers complex scalp defects but doesn't improve survival for cancer-related cases.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.

Creating a natural-looking hairline in hair restoration surgery involves using follicular unit grafts, proper hair placement, and artistic skills to give the illusion of density.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.