11 citations
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October 2015 in “Clinical and Experimental Dermatology” This study found that an extract from the root of Sophora flavescens Aiton significantly improved hair growth in patients with androgenetic alopecia over 6 months.
11 citations
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March 2014 in “Journal of The European Academy of Dermatology and Venereology” In this study, researchers found that androgen receptor gene polymorphism is associated with higher androgenetic alopecia grades and PSA levels in men with benign prostatic hyperplasia, but not with prostate cancer.
10 citations
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May 2021 in “Stem Cell Research & Therapy” In this study, subcutaneous injection of bone marrow mesenchymal stem cells in burned rats significantly improved wound healing by reducing inflammation, scar formation, and wound size, and restoring normal skin structures.
3 citations
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March 2018 in “BMC Cancer” This study found that androgenic alopecia was associated with a decreased risk of testicular germ cell tumors but a potential increased risk of high-grade prostate cancer.
This case report describes a 21-year-old man with alopecia areata presenting as a U-shaped hair loss pattern resembling Hamilton grade VII male-pattern baldness, with no signs of inflammation or related conditions.
December 2025 in “Reports of Vinnytsia National Medical University” This study examined the relationships between the Dermatology Life Quality Index and trichoscopic and clinical-anamnestic characteristics in young Ukrainian men with alopecia areata, finding varying strengths of mostly non-significant correlations, especially in those with grade I and III alopecia.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study evaluated current treatments for pediatric alopecia areata and found that high potency topical steroids had the strongest supporting evidence, with promising results also observed for anthralin ointment and other treatments in lower-grade studies.
18 citations
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January 2017 in “Annals of dermatology/Annals of Dermatology” This study found that Th17 lymphocytes may play a more crucial role than cytotoxic T cells in the development of alopecia areata due to their infiltration around the hair bulb/bulge, which exacerbates hair loss as histopathological grade worsens.
5 citations
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September 2020 in “Journal of The American Academy of Dermatology” This study reported that low-dose oral minoxidil combined with a 5α-reductase inhibitor improved hair density in most men with female pattern hair loss after 6 months or more of treatment.
45 citations
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May 2018 in “Stem Cell Research & Therapy” In this study, patients receiving adipose-derived stromal vascular cell transplantation for alopecia areata experienced significant hair regeneration, increased growth, and improved hair quality after 3 and 6 months, indicating potential efficacy of this stem cell-based therapy for hair loss.
February 2025 in “Journal of the American Academy of Dermatology” Standardized treatment protocols are needed for children with androgenetic alopecia.
27 citations
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October 2001 in “Journal of Medicinal Chemistry” This study identified eight isoflavone derivatives as potential nonsteroidal inhibitors of rat 5α-reductase using a pharmacophore model in virtual screening.
August 2024 in “Research Square (Research Square)” This study found that women taking 5α-reductase inhibitors (5aRI) for alopecia had a lower risk of breast cancer compared to those not using these medications, with no increased risk of developing ovarian or endometrial cancer.
July 2025 in “The Lancet Regional Health - Southeast Asia” This Health Policy report outlines the creation of evidence-based clinical practice guidelines and referral pathways for managing dermatological conditions in Pakistan's primary care setting, aiming to standardize care and improve patient outcomes.
January 2022 in “Cosmoderma” This study found that combining oral minoxidil with dutasteride increased hair thickness, density, and new growth in male pattern baldness patients with minimal side effects.
1 citations
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February 2023 in “Drug Design Development and Therapy” This review discusses the dermatological effects and potential mechanisms of plant adaptogens, emphasizing their role in skin health and aging without presenting new experimental results.
7 citations
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January 2022 in “Scientific Reports” This study found that Acanthus ebracteatus extract and verbascoside induced dermal papilla cell proliferation and reduced inflammatory cytokine release in vitro, suggesting potential for anti-hair loss applications.
March 2021 in “Indian Journal of Dermatology” A man unhappy with his old hair restoration got a new, natural-looking hairline using a combination of follicular unit extraction and punch graft reduction.
July 2023 in “Journal of Microbiology and Biotechnology” This study found that oral administration of Terminalia bellirica enhanced hair growth in testosterone-suppressed conditions in both human cell and mouse models, outperforming finasteride, a current commercial hair loss treatment.
January 2026 in “Dermatologic Therapy” This study found that a hair serum containing Acanthus ebracteatus extract improved hair regrowth in men with androgenic alopecia, increasing hair count and density of anagen hairs over a 6-month period, with combination treatments showing early effectiveness.
53 citations
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August 2014 in “Cochrane library” This review found no evidence supporting the efficacy of methotrexate for inducing remission in active ulcerative colitis compared to placebo or active comparators.
51 citations
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August 2015 in “Cochrane library” This systematic review reports that there is currently no evidence supporting methotrexate for maintaining remission in ulcerative colitis; further large-scale trials are needed to assess its efficacy and safety.
33 citations
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January 2009 in “Journal of Cutaneous and Aesthetic Surgery” This study found no clear evidence that finasteride negatively affects erectile function, though it does cause a reduction in ejaculatory volume and has potential implications for prostate cancer risk.
2 citations
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May 2025 in “IntechOpen eBooks” This article highlights that early and high-dose corticosteroid therapy, along with immunosuppressive agents, is crucial for managing Vogt-Koyanagi-Harada disease, and emerging biological therapies may benefit refractory cases.
January 2026 in “Materialia” In this study, porcine collagen acellular dermal matrix scaffolds combined with mice platelet-rich plasma were associated with increased hair density and follicle regeneration in mice with alopecia, suggesting a potential therapeutic approach.
July 2024 in “Skin Appendage Disorders” This study found that after 6 months of taking an oral supplement, patients with chronic telogen effluvium or androgenetic alopecia experienced a statistically significant increase in hair density and overall improved hair appearance compared to those taking a placebo, with the supplement being well tolerated.
May 2019 in “Journal of clinical oncology” This study found that concurrent chemotherapy with radiotherapy may increase the risk of grade 2 persistent radiation-induced alopecia, while topical minoxidil showed potential benefits, though more research is needed on its efficacy.
8 citations
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January 2016 in “Cells tissues organs” This study found that chemical sympathectomy inhibited hair follicle growth in mice, suggesting that sympathetic nerves may regulate keratinocyte behavior to promote hair growth.
September 2024 in “Journal of Microbiology and Biotechnology” In this study, the researchers found that their conductive bio-harvesting tonic enhanced hair follicle proliferation and delayed regression with electric stimulation and the antifungal agent 6-pentyl-α-pyrone in both mice and human hair follicle tests.
2 citations
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February 2014 in “Journal of Crohn's and colitis” This study observed that 6.45% of IBD patients treated with anti-TNF therapy developed severe psoriasiform reactions, with notable cases of alopecia universalis suggesting a potential link to previous alopecia areata.