research Inherited Ichthyoses: Generalized Mendelian Disorders of Cornification
Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.
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research Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency
Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
research Doxil (Caelyx): An Exploratory Study with Pharmacokinetics in Patients with Hormone-Refractory Prostate Cancer
Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.
research Methotrexate in the Treatment of Steroid-Dependent Asthma
Methotrexate reduced the need for steroids in asthma patients without worsening their condition.
research Topical Minoxidil in the Treatment of Alopecia Areata
Minoxidil helps hair regrowth in alopecia patients, with 16 having good results and no side effects.
research Quality of Life, Burden of Disease, Comorbidities, and Systemic Effects in Vitiligo Patients
Vitiligo affects overall health and self-esteem, needing more research and awareness.
research Diet and Hair Loss: Effects of Nutrient Deficiency and Supplement Use
Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.
research Case Series of Selenium Toxicity from a Nutritional Supplement
Excessive selenium from a supplement caused toxicity but patients recovered with care.
research Alopecia Areata Treated With Topical Minoxidil
Minoxidil can help regrow hair in alopecia areata patients.
research Clinical and Biological Impact of the Exposome on the Skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
research Emerging Medication for the Treatment of Male Hypogonadism
New treatments for male hypogonadism are effective and should be personalized.
research Adipose-Derived Stromal Cells in Regenerative Medicine: A Review
Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.
research Pilosebaceous Physiology in Relation to Hirsutism and Acne
Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.
research Minoxidil: An Underused Vasodilator for Resistant or Severe Hypertension
Minoxidil effectively treats severe hypertension, but watch for side effects.
research Repurposing of Approved Cardiovascular Drugs
Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.
research Ovarian Morphology Is a Marker of Heritable Biochemical Traits in Sisters with Polycystic Ovaries
Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.
research Niosomes as a Promising Carrier for Topical Drug Delivery
Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.
research Improving Stable Isotopic Interpretations Made From Human Hair Through Reduction of Growth Cycle Error
The conclusion is that recognizing hair growth cycles can improve the precision of dietary and health assessments from hair analysis.
research The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen, and Sexual Function in Healthy Young Men
Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
research Wnt Signaling in Skin Organogenesis
Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
research The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function
A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.
research Regeneration of Skin Appendages and Nerves: Current Status and Further Challenges
Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
research Physical Changes, Laboratory Parameters, and Bone Mineral Density During Testosterone Treatment in Adolescents with Gender Dysphoria
Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.
research P53 Involvement in the Control of Murine Hair Follicle Regression
The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
research The Emerging Role of Janus Kinase Inhibitors in the Treatment of Autoimmune and Inflammatory Diseases
Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
research Prevalence of Functional Disorders of Androgen Excess in Unselected Premenopausal Women: A Study in Blood Donors
Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.
research Ectopic Expression of the Nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia
The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
research Combined Sabal And Urtica Extract Vs Finasteride In Benign Prostatic Hyperplasia (Alken Stage I–II)
Sabal and Urtica extract works as well as finasteride for treating BPH, with fewer side effects.
research The Role of Nuclear Hormone Receptors in Cutaneous Wound Repair
Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
research Revising the Role of the Androgen Receptor in Breast Cancer
The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.