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A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

Biologics show promise in treating various stubborn skin diseases, but more research and better reimbursement criteria are needed.

The study found that in Latin America, ancestry varies by location, influences physical traits, and affects how people perceive their own heritage.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

Lower SHBG levels may increase the risk of PCOS.

A boy with progeria had eye problems and signs of aging like hair loss and skin wrinkling.

Different STUB1 gene mutations cause varied symptoms in autosomal recessive ataxias.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.

Early diagnosis and treatment are key to managing health risks in teens with PCOS.

Women with PCOS in Sicily show different levels of metabolic problems depending on their PCOS type, with obesity and abnormal lipid profiles being common.

Older obese women with PCOS have higher cardiovascular and metabolic risks despite lower androgen levels.

Diagnosing and managing PCOS in teens is hard, but early diagnosis and lifestyle changes are key, and more research is needed for long-term health.

A 6-year-old girl with Turner syndrome also had psoriasis, alopecia areata, and trachyonychia.

People with male pattern baldness are more likely to have metabolic syndrome.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

A new MTX2 gene mutation caused a severe genetic disorder in a young Chinese girl.

People with plantar corns and calluses may have a higher chance of having metabolic syndrome.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Early balding in men is linked to metabolic syndrome, so screening is important for prevention.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.