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Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Gene mutations can cause problems in male genital development.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Ovarian vein sampling helped diagnose rare ovarian tumors causing high testosterone, and surgery to remove the tumors lowered the testosterone levels.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

Antiandrogens are the main treatment for hirsutism, with individualized care and safe, affordable options needed.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

The conclusion is that lifestyle changes and weight loss are first-line treatments for infertility due to anovulation, with various medications and assisted reproductive technologies as additional options.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.

Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.

Lifestyle changes like diet and exercise are key for treating overweight women with polycystic ovary syndrome.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

The document concludes that PCOS in adolescents is complex and requires comprehensive care to manage its symptoms and associated health risks.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.