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In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Prolactin may be important for skin growth and immune function.

Oral contraceptives may cause hair loss in women.

Isotretinoin may cause temporary, reversible facial hair growth in some women.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Subcutaneous contraceptives can cause side effects like menstrual changes, headaches, weight gain, and pain at the implant site.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.

Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.

Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.

Metformin and thiazolidinediones are similarly effective for PCOS, but metformin is often preferred due to fewer side effects.

Clomiphene citrate improves fertility in men taking finasteride for hair loss.

High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

PCOS is a hormonal disorder causing infertility and menstrual problems, often linked to obesity and can lead to acne, treated with hormonal and insulin-sensitizing medications.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.

No cure for female pattern hair loss, but various effective treatments exist.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Spironolactone plus finasteride reduces hirsutism more effectively.