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Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Lower SHBG levels may increase the risk of PCOS.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

New treatments for male hypogonadism are effective and should be personalized.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Neurosteroids show promise for treating epilepsy and more research is needed.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

A male with aromatase deficiency improved bone health with estradiol treatment.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.

Diet changes can help reduce acne by limiting certain hormones.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Certain drugs change freshwater snail shells to a "banana" shape.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

DHT affects testicular development and regulates spermatogenesis in some fish.