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The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

The document covers various male health issues, their causes, treatments, and related conditions.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Longer hair loss leads to more severe CCCA; early treatment and avoiding damaging hairstyles help regrowth.

Pregnancy reduces anxiety in rats, but finasteride reverses this effect.

Finasteride exposure harms tadpole reproduction and hormone balance.

A patient with Satoyoshi syndrome improved with a treatment combining several medications, including carbamazepine and methotrexate.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

Triptorelin helps evaluate hormone production in Sertoli-Leydig cell tumors.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.

Hair loss has many causes and treatments, and losing some hair daily is normal; proper diagnosis is key, and minoxidil can help treat it.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

New genes and pathways are important for testosterone production and male sexual development.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Neutered ferrets often develop hyperadrenocorticism, with symptoms like hair loss and lethargy, and androstenedione is a key indicator for diagnosis.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Sex hormones, especially androgens, play a key role in causing acne.

Hair analysis for stress and reproductive hormones in wildlife needs more research for accuracy across species.

Gut microbes significantly affect brain steroid levels.

Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.