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Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

Steroid hormones can help treat aging issues and improve health in elderly people.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Lowering testosterone speeds up wound healing in male mice.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Statins may be linked to reproductive organ conditions, and their risks should be monitored.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

High levels of cortisol in hair show long-term stress which can lower fertility in animals.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Oestrogens are key for bone growth during puberty in both boys and girls.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.