58 citations,
June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.
28 citations,
May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.
317 citations,
April 2018 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
93 citations,
February 2009 in “Annals of the New York Academy of Sciences” 5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
31 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
27 citations,
April 2013 in “Reviews in endocrine and metabolic disorders” The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
5 citations,
November 1992 in “Current problems in dermatology” Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
1 citations,
January 2017 in “Tohoku journal of experimental medicine” A woman's mature cystic teratoma caused her virilization by producing testosterone.
75 citations,
November 1996 in “Fertility and Sterility” Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
30 citations,
January 2000 in “Dermatologic Clinics” Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
29 citations,
January 2006 in “Clinical chemistry and laboratory medicine” SHBG binding properties are unchanged in male liver cirrhosis patients.
24 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
22 citations,
March 2000 in “Clinics in Dermatology” Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
13 citations,
November 2019 in “Scientific reports” Certain drugs change freshwater snail shells to a "banana" shape.
7 citations,
January 1992 in “Adolescent and pediatric gynecology” Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.
4 citations,
January 2013 in “PubMed” Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.
1 citations,
March 2011 in “Infertility” Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.
173 citations,
May 2001 in “Human reproduction update” Oestrogens are key for bone growth during puberty in both boys and girls.
65 citations,
January 2011 in “Frontiers in Endocrinology” Neurosteroids show promise for treating epilepsy and more research is needed.
65 citations,
October 2008 in “Journal of Neuroendocrinology” 53 citations,
October 1984 in “Endocrine reviews” Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
40 citations,
December 2012 in “Epilepsia” Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
30 citations,
July 2019 in “Endocrinology” Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.
25 citations,
June 2017 in “Molecular and Cellular Endocrinology” Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
16 citations,
February 2018 in “European Journal of Endocrinology” Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
16 citations,
September 2008 in “Dermatologic Therapy” CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.
15 citations,
August 2016 in “Current Urology Reports” Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.
13 citations,
June 1989 in “Pediatric clinics of North America/The Pediatric clinics of North America” The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.
12 citations,
December 2017 in “Scientific reports” The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.
11 citations,
January 2017 in “Journal of Endocrinology/Journal of endocrinology” Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.