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Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Genetics affect early female hair loss, severity depends on duration, and low ferritin levels not significant.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Antiandrogen therapies are beneficial for treating skin and hair conditions related to androgen levels.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

Diazoxide applied to the skin can increase hair growth without harmful side effects.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Certain gene variations are linked to better memory in healthy Chinese women.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.

PSA might help diagnose PCOS and related skin issues, but more research is needed.

Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.

Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.

Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Both mouse and rat models are effective for testing alopecia areata treatments.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.