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The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Childhood ptosis can vary from a minor cosmetic issue to a serious condition and may signal other health problems.

Finasteride may cause kidney damage.

A 38-year-old man was diagnosed late with Kearns-Sayre syndrome after being wrongly treated for epilepsy.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Gene mutations can cause problems in male genital development.

Muscles can make their own androgens, which may help muscle growth.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.

Quercetin may help improve symptoms of polycystic ovary syndrome.

Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.

Sertraline, an antidepressant, may cause hair loss in rare cases.

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document advises health care providers on how to support transgender and gender-diverse youth with appropriate care and referrals.

Genomic approach finds new possible treatments for hair loss.

Heat treatment increases hair loss in certain mice.

Hormones and genes affect hair growth and male baldness.

Finasteride use can cause depression-like behavior in male rats.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Hormone therapy for trans individuals is effective and generally safe in the short term.