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Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.

Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.

Hirsutism involves excessive hair growth due to hormonal issues and can be treated with medication or surgery.

A complex X chromosome rearrangement can increase the risk of multiple autoimmune diseases.

A genetic mutation in the DCAF17 gene caused Woodhouse-Sakati syndrome in a Chinese patient from a related family.

A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.

Foxn1 is important for fat development, metabolism, and wound healing in skin.

Effective acne treatments should reduce sebum, bacteria, and inflammation, with isotretinoin being the best for severe cases.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Sex hormones, especially androgens, play a key role in causing acne.

Women with Polycystic Ovary Syndrome have higher levels of the hormone ghrelin, which may be linked to the cause of the condition.

Hair analysis for stress and reproductive hormones in wildlife needs more research for accuracy across species.

Puberty involves complex hormonal changes, varies by gender and ethnicity, and requires careful monitoring for abnormalities.

Indinavir can cause hair loss and other skin problems.

Turner's syndrome may be linked to autoimmune diseases like psoriasis and alopecia areata, needing comprehensive care.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

Old drugs are often used for new, different medical purposes in endocrine pharmacology.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Girls had higher stress hormone levels during school due to social and emotional issues, while boys had higher overall hormone levels with slight changes when school started.

Methylphenidate can cause hair loss, which stops when the drug is discontinued.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

Understanding how acne develops in different diseases could lead to new treatments.