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A new mutation in the DCAF17 gene was found in a Chinese family, causing Woodhouse-Sakati syndrome and diabetes.

Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

A child with trichothiodystrophy also had autoimmune thyroiditis and anemia, which is a new finding.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Skin symptoms can indicate endocrine disorders and have various treatments.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Certain gene variations are linked to better memory in healthy Chinese women.

Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Testicular microlithiasis may increase the risk of testicular cancer and patients with it should be closely monitored.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.