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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Hirsutism is when women have too much hair growth, often due to a bit more androgen hormones and sensitive skin.

Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.

Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

Acne is a chronic skin condition not caused by poor hygiene or diet, and it requires long-term treatment and patient education.

A young woman with kidney failure had hair loss due to a common hormonal disorder, which improved with hormone therapy.

Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.

Testosterone may influence COVID-19 severity and outcomes.

Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.

Lowering testosterone speeds up wound healing in male mice.

Metabolic syndrome linked to urinary symptoms; hair loss not significant.

The conclusion is that adult males with muscle weakness and hormonal imbalances should be tested for Kennedy's disease.

Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.

Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.

Higher androstenedione levels in women with PCOS are linked to more severe symptoms.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.

Women with PCOS and polycystic ovaries have higher male hormone levels and more insulin resistance, especially if they are overweight.

The document concludes that accurate diagnosis and management of PCOS are crucial due to its associated health risks.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Removing both ovaries treated the woman's excess male hormone symptoms.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.

Tamoxifen can cause total hair loss but its benefits outweigh this side effect.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.